Key features and details
- Gap junction inhibitor
- CAS Number: 471-53-4
- Purity: > 98%
- Soluble in ethanol
- Form / State: Solid
- Source: Synthetic
Product name18beta-Glycyrrhetinic acid (Enoxolone), Gap junction inhibitor
DescriptionGap junction inhibitor
Biological descriptionGap junction inhibitor. Antiviral activity against rotavirus replication in vitro. Shows immunomodulatory, chemopreventive and anti-inflammatory effects in vivo. Orally active.
Chemical name(2S,4aS,6aR,6aS,6bR,8aR,10S,12aS,14bR)-10-hydroxy-2,4a,6a,6b,9,9,12a-heptamethyl-13-oxo-3,4,5,6,6a,7,8,8a,10,11,12,14b-dodecahydro-1H-picene-2-carboxylic acid
Storage instructionsStore at Room Temperature. The product can be stored for up to 12 months.
Solubility overviewSoluble in ethanol
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
- Pathways and Processes
- Metabolic signaling pathways
- Lipid and lipoprotein metabolism
- Lipid metabolism
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
ab142579 has been referenced in 1 publication.
- Schultz ML et al. Modulating membrane fluidity corrects Batten disease phenotypes in vitro and in vivo. Neurobiol Dis 115:182-193 (2018). PubMed: 29660499