Product name2-Acetamido-1,2-dideoxynojirimycin, N-acetylglucosaminidase inhibitor
DescriptionPotent inhibitor of a number of N-acetylglucosaminidases
Deoxynojirimycin analog. Potent inhibitor of a number of N-acetylglucosaminidases (Ki = 0.45 µM for human alpha-N-acetylglucosaminidase).
Storage instructionsStore at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.
Silightly soluble in water
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
This product has been referenced in:
- de la Fuente A et al. Stereoselective synthesis of 2-acetamido-1,2-dideoxynojirimycin (DNJNAc) and ureido-DNJNAc derivatives as new hexosaminidase inhibitors. Org Biomol Chem 13:6500-10 (2015). Read more (PubMed: 25975710) »
- Kim YK et al. Suppression of beta-N-acetylglucosaminidase in the N-glycosylation pathway for complex glycoprotein formation in Drosophila S2 cells. Glycobiology 19:301-8 (2009). Read more (PubMed: 19054802) »
- Zhao KW & Neufeld EF Purification and characterization of recombinant human alpha-N-acetylglucosaminidase secreted by Chinese hamster ovary cells. Protein Expr Purif 19:202-11 (2000). Read more (PubMed: 10833408) »
- Böshagen H et al. The chemistry of the 1-deoxynojirimycin system. Synthesis of 2-acetamido-1,2-dideoxynojirimycin from 1-deoxynojirimycin. Carbohydr Res 164:141-8 (1987). Read more (PubMed: 2957054) »