Key features and details
- Highly potent, selective A1 agonist
- CAS Number: 37739-05-2
- Purity: > 98%
- Soluble in water to 5 mM and in DMSO to 100 mM
- Form / State: Solid
- Source: Synthetic
Product name2-Chloro-N6-cyclopentyladenosine (CCPA), A1 agonist
DescriptionHighly potent, selective A1 agonist
Highly potent and selective A1 receptor agonist (Ki values are 0.8, 2300 and 42 nM for human A1, A2A and A3 receptors, respectively). Shows >2000-fold selectivity over A2A. Centrally active following systemic administration and anticonvulsive in vivo.
Storage instructionsStore at Room Temperature. Store under desiccating conditions. The product can be stored for up to 12 months.
Solubility overviewSoluble in water to 5 mM and in DMSO to 100 mM
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
ab120434 has been referenced in 2 publications.
- Fujimoto K et al. Adenosine Attenuates Aortic Smooth Muscle Cell Calcification through A3 Adenosine Receptor. Tohoku J Exp Med 249:275-283 (2019). PubMed: 31875581
- Yi X et al. Adenosine receptors enhance the ATP-induced odontoblastic differentiation of human dental pulp cells. Biochem Biophys Res Commun 497:850-856 (2018). PubMed: 29454963