Product name2'-Deoxyguanosine 5'-monophosphate disodium salt, guanylate kinase substrate
DescriptionGuanylate kinase substrate
- 2'-Deoxy-5'-guanylic acid disodium salt
- 2'-Deoxy-D-guanosine-5'-monophosphate disodium salt
- 2'-dGMP 2Na
Used as a substrate of guanylate kinases to generate dGDP, which in turn is phosphorylated to dGTP, a nucleotide precursor used in DNA synthesis.
Storage instructionsStore at +4°C. Store under desiccating conditions. The product can be stored for up to 12 months.
Solubility overviewSoluble in water
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
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This product has been referenced in:
- Grabmann G et al. A systematic capillary electrophoresis study on the effect of the buffer composition on the reactivity of the anticancer drug cisplatin to the DNA model 2'-deoxyguanosine 5'-monophosphate (dGMP). Anal Bioanal Chem 405:6417-24 (2013). Read more (PubMed: 23620371) »
- Mariani P et al. Small angle X-ray scattering analysis of deoxyguanosine 5'-monophosphate self-assembing in solution: nucleation and growth of G-quadruplexes. J Phys Chem B 113:7934-44 (2009). Read more (PubMed: 19435359) »