Product name2'-Deoxyuridine-5'-monophosphate disodium salt, reference substrate for dUMP analogs
DescriptionReference substrate for dUMP analogs.
- 2'-Deoxy-5'-uridylic acid disodium salt
- dUMP disodium salt
Used by the enzyme thymidylate synthetase (TS) (EC 188.8.131.52) for the de novo production of dTMP. Reference substrate in studies of dUMP analogs in potential chemotherapy applications.
Storage instructionsStore at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.
Solubility overviewSoluble in water to 10 mM
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
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This product has been referenced in:
- Koehn EM et al. An unusual mechanism of thymidylate biosynthesis in organisms containing the thyX gene. Nature 458:919-23 (2009). Read more (PubMed: 19370033) »