Key features and details
- Potent and selective PAR2 agonist
- CAS Number: 729589-58-6
- Purity: > 95%
- Soluble in water to 1 mg/ml
- Form / State: Solid
- Source: Synthetic
Product name2-Furoyl-LIGRLO-amide (2Fly), PAR2 agonist
DescriptionPotent and selective PAR2 agonist
Biological descriptionPotent and selective PAR2 receptor agonist (EC50 = 340 nM). Induces arterial contraction. Facilitates capsaicin evoked nociception. Around 100 times more potent than SLIGR-NH2 (ab120176).
SequenceLIGRLX (Modifications: N-terminal 2-Furoyl; C-terminal amide; X-6 = Orn)
Storage instructionsStore at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.
Solubility overviewSoluble in water to 1 mg/ml
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one week. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
ab120800 has not yet been referenced specifically in any publications.