2-Heptyl-3-hydroxy-4-quinolone, Intercellular signal compound (ab145430)

Overview

  • Product name

    2-Heptyl-3-hydroxy-4-quinolone, Intercellular signal compound
  • Description

    Intercellular signal compound.
  • Alternative names

    • 2-Heptyl-3-hydroxy-4(1H)-quinolone
    • PQS
    • Pseudomonas quinolone signal
  • Biological description

    Quorum sensing signaling molecule used to induce and study the regulation of virulence genes. Quorum sensing is a signaling system used by bacteria to coordinate activity based upon their population density. The system involves the exchange of signaling molecules among bacteria via cell receptors.

  • Purity

    > 96%
  • CAS Number

    108985-27-9
  • Chemical structure

    Chemical Structure

Properties

  • Molecular weight

    259.34
  • Molecular formula

    C16H21NO2
  • Storage instructions

    Store at Room Temperature. Store under desiccating conditions. The product can be stored for up to 12 months.
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • Source

    Synthetic

References

This product has been referenced in:

  • Soh EY  et al. Biotic inactivation of the Pseudomonas aeruginosa quinolone signal molecule. Environ Microbiol 17:4352-65 (2015). Read more (PubMed: 25809238) »
  • Pesci EC  et al. Quinolone signaling in the cell-to-cell communication system of Pseudomonas aeruginosa. Proc Natl Acad Sci U S A 96:11229-34 (1999). Read more (PubMed: 10500159) »

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Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES, NOT FOR USE IN HUMANS"
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