Key features and details
- Cytochrome P450 metabolite of estradiol
- CAS Number: 362-05-0
- This product is soluble in ethanol, DMSO, and DMF to about 20 mg/ml.
- Form / State: Solid
- Source: Synthetic
Product name2-Hydroxyestradiol, Cytochrome P450 metabolite of estradiol
DescriptionCytochrome P450 metabolite of estradiol
Biological descriptionCytochrome P450 metabolite of estradiol with low affinity for estrogen receptors. Stimulates increase in β-adrenergic receptor density. Biological effects mediated by 2-methoxyestradiol after methylation of 2OHE by catechol-O-methyltransferase (COMT). Active in vivo and in vitro.
Storage instructionsShipped at Room Temperature. Store at -20°C. The product can be stored for up to 12 months.
Solubility overviewThis product is soluble in ethanol, DMSO, and DMF to about 20 mg/ml.
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
ab142519 has not yet been referenced specifically in any publications.