2-NBD-Glucose, Fluorescent glucose uptake probe (ab146200)
Key features and details
- Cell-permeable fluorescent glucose uptake probe
- CAS Number: 186689-07-6
- Soluble in ethanol to 50 mM and in DMSO to 25 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
2-NBD-Glucose, Fluorescent glucose uptake probe -
Description
Cell-permeable fluorescent glucose uptake probe -
Alternative names
- 2-(N-(7-Nitrobenz-2-oxa-1,3-diazol-4-yl)Amino)-2-Deoxyglucose
- 2-NBDG
- NBD-Glucose
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CAS Number
186689-07-6 -
Chemical structure
Properties
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Excitation
465nm -
Emission
540nm -
Molecular weight
342.26 -
Molecular formula
C12H14N4O8 -
Storage instructions
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in ethanol to 50 mM and in DMSO to 25 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Refer to SDS for further information.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
c1cc(c2c(c1N[C@@H]3[C@H]([C@@H]([C@H](OC3O)CO)O)O)non2)[N+](=O)[O-] -
Source
Synthetic
Protocols
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
Datasheets and documents
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SDS download
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Datasheet download
References (5)
ab146200 has been referenced in 5 publications.
- Baier D et al. The Anticancer Ruthenium Compound BOLD-100 Targets Glycolysis and Generates a Metabolic Vulnerability towards Glucose Deprivation. Pharmaceutics 14:N/A (2022). PubMed: 35213972
- Oburoglu L et al. Pyruvate metabolism guides definitive lineage specification during hematopoietic emergence. EMBO Rep 23:e54384 (2022). ICC ; Mouse . PubMed: 34914165
- Li SR et al. Glucose absorption drives cystogenesis in a human organoid-on-chip model of polycystic kidney disease. Nat Commun 13:7918 (2022). PubMed: 36564419
- Gifford EK et al. Validation of Dexamethasone-Enhanced Continuous-Online Microdialysis for Monitoring Glucose for 10 Days after Brain Injury. ACS Chem Neurosci 12:3588-3597 (2021). PubMed: 34506125
- Cossarizza A et al. Guidelines for the use of flow cytometry and cell sorting in immunological studies (second edition). Eur J Immunol 49:1457-1973 (2019). PubMed: 31633216