20(S)-Ginsenoside Rh2, Active component of red ginseng (ab141935)

Overview

  • Product name

    20(S)-Ginsenoside Rh2, Active component of red ginseng
  • Description

    Active component of red ginseng
  • Biological description

    Active component of red ginseng. Induces cell cycle arrest and apoptosis and displays immunomodulatory and antimetastatic activity in vitro and in vivo.
  • Purity

    > 98%
  • CAS Number

    78214-33-2
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    (3β,12β)-12,20-Dihydroxydammar-24-2n-3-yl β-D-glucopyranoside
  • Molecular weight

    622.87
  • Molecular formula

    C36H62O8
  • PubChem identifier

    119307
  • Storage instructions

    Store at +4°C. The product can be stored for up to 12 months.
  • Solubility overview

    Soluble in ethanol to 10 mM
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    CC(=CCCC(C)(C1CCC2(C1C(CC3C2(CCC4C3(CCC(C4(C)C)OC5C(C(C(C(O5)CO)O)O)O)C)C)O)C)O)C
  • Source

    Panax sp.

  • Research areas

References

This product has been referenced in:

  • Chung KS  et al. Ginsenoside Rh2 induces cell cycle arrest and differentiation in human leukemia cells by upregulating TGF-ß expression. Carcinogenesis 34:331-40 (2013). Read more (PubMed: 23125221) »
  • He L  et al. Ginsenoside Rh2 inhibits osteoclastogenesis through down-regulation of NF-?B, NFATc1 and c-Fos. Bone 50:1207-13 (2012). Read more (PubMed: 22484180) »
  • Fei XF  et al. Apoptotic effects of ginsenoside Rh2 on human malignant melanoma A375-S2 cells. Acta Pharmacol Sin 23:315-22 (2002). Read more (PubMed: 11931705) »

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