Product name2,2'-Bipyridine, Metalloprotease inhibitor
DescriptionMetalloprotease inhibitor; high-affinity chelator of iron.
Symmetrical bipyridine commonly used as a neutral ligand for chelating with metal ions. Metalloprotease inhibitor. High-affinity chelator of iron. May inhibit Fe2+ containing enzymes at 10−8 M.
Storage instructionsStore at Room Temperature. Store under desiccating conditions. The product can be stored for up to 12 months.
Solubility overviewSoluble in ethanol
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Toxic, refer to SDS for further information.
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This product has been referenced in:
- Correia I et al. Vanadium(IV) and copper(II) complexes of salicylaldimines and aromatic heterocycles: Cytotoxicity, DNA binding and DNA cleavage properties. J Inorg Biochem 147:134-46 (2015). Read more (PubMed: 25858461) »
- Filho JC et al. Copper (II) and 2,2'-bipyridine complexation improves chemopreventive effects of naringenin against breast tumor cells. PLoS One 9:e107058 (2014). Read more (PubMed: 25192075) »
- Hassanein WA et al. Fibrinolysis and anticoagulant potential of a metallo protease produced by Bacillus subtilis K42. J Biosci 36:773-9 (2011). Read more (PubMed: 22116275) »