3-Deazaneplanocin A (DMSO solution), S-adenosylhomocysteine hydrolase (ab146627)

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Chemical Structure - 3-Deazaneplanocin A (DMSO solution), S-adenosylhomocysteine hydrolase (ab146627)

    Key features and details

    • Potent S-adenosylhomocysteine hydrolase (SAHH) and histone methyltransferase (HMT) inhibitor
    • CAS Number: 102052-95-9
    • Purity: > 98%
    • Supplied in DMSO (10 mM)
    • Form / State: Liquid
    • Source: Synthetic

    Overview

    • Product name

      3-Deazaneplanocin A (DMSO solution), S-adenosylhomocysteine hydrolase

    • Description

      Potent S-adenosylhomocysteine hydrolase (SAHH) and histone methyltransferase (HMT) inhibitor

    • Biological description

      Potent S-adenosylhomocysteine hydrolase (SAHH) and histone methyltransferase (HMT) inhibitor. Induces cancer cell selective apoptosis. Shows antitumor effects in vivo.

      Also available as a solid (ab142215).

    • Purity

      > 98%

    • CAS Number

      102052-95-9

    • Chemical structure

      Chemical Structure

    Properties

    • Chemical name

      (1S,2R,5R)-5-(4-Aminoimidazo[4,5-c]pyridin-1-yl)-3-(hydroxymethyl)cyclopent-3-ene-1,2-diol

    • Molecular weight

      262.26

    • Molecular formula

      C12H14N4O3

    • PubChem identifier

      73087

    • Storage instructions

      Store at -20°C. Store In the Dark. Store under desiccating conditions. This product is air and light sensitive and impurities can occur as a result of air oxidation or due to metabolism by microbes.

    • Solubility overview

      Supplied in DMSO (10 mM)

    • Handling

      Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

      Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

    • SMILES

      C1=CN=C(C2=C1N(C=N2)[C@@H]3C=C([C@H]([C@H]3O)O)CO)N

    • Source

      Synthetic

    • Research areas

    Images

    • Chemical Structure - 3-Deazaneplanocin A (DMSO solution), S-adenosylhomocysteine hydrolase (ab146627)
      Chemical Structure - 3-Deazaneplanocin A (DMSO solution), S-adenosylhomocysteine hydrolase (ab146627)
      2D chemical structure image of ab146627, 3-Deazaneplanocin A (DMSO solution), S-adenosylhomocysteine hydrolase

    Protocols

    To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

    Click here to view the general protocols

    References (0)

    Publishing research using ab146627? Please let us know so that we can cite the reference in this datasheet.

    ab146627 has not yet been referenced specifically in any publications.

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