Overview

  • Product name

    3-Formylrifamycin, Rifamycin derivative antibiotic
  • Description

    Rifamycin derivative antibiotic
  • Biological description

    Rifamycin derivative antibiotic. Interacts with biological membranes. Alters permeability to K+ and H+ in the mitochondrial membrane.Orally active.
  • Purity

    > 98%
  • CAS Number

    13292-22-3
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    1,2-Dihydro-5,6,9,17,19,21-hexahydroxy-23-methoxy-2,4,12,16,18,20,22-heptamethyl-1,11-dioxo-2,7-(epoxypentadeca(1,11,13)trienimino)naphtho(2,1-b)furan-8-carboxaldehyde 21-acetate
  • Molecular weight

    725.78
  • Molecular formula

    C38H47NO13
  • PubChem identifier

    6438444
  • Storage instructions

    Store at Room Temperature. The product can be stored for up to 12 months.
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    CC1C=CC=C(C(=O)NC2=C(C3=C(C4=C(C(=C3O)C)OC(C4=O(OC=CC(C(C(C(C(C(C1O)C)O)C)OC(=O)C)C)OC)C)C(=C2C=O)O)O)C
  • Source

    Synthetic

  • Research areas

References

This product has been referenced in:

  • Prasad B & Singh S LC-MS/TOF and UHPLC-MS/MS study of in vivo fate of rifamycin isonicotinyl hydrazone formed on oral co-administration of rifampicin and isoniazid. J Pharm Biomed Anal 52:377-83 (2010). Read more (PubMed: 19692195) »
  • Emary WB  et al. Disposition and metabolism of rifapentine, a rifamycin antibiotic, in mice, rats, and monkeys. Drug Metab Dispos 26:725-31 (1998). Read more (PubMed: 9698285) »
  • Tsai MJ & Saunders GF Action of rifamycin derivatives on RNA polymerase of human leukemic lymphocytes. Proc Natl Acad Sci U S A 70:2072-6 (1973). Read more (PubMed: 4516206) »

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Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES, NOT FOR USE IN HUMANS"
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