3-Ketodihydrosphingosine hydrochloride, Ceramide biosynthesis intermediate (ab144107)

Overview

  • Product name

    3-Ketodihydrosphingosine hydrochloride, Ceramide biosynthesis intermediate
  • Description

    Necessary intermediate in ceramide biosynthesis
  • Alternative names

    • 3-Ketosphinganine hydrochloride
  • Biological description

    Necessary intermediate in ceramide (ab141745, ab141743) biosynthesis.
  • Purity

    > 98%
  • CAS Number

    18944-28-0
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    (2S)-2-Amino-1-hydroxyoctadecan-3-one hydrochloride
  • Molecular weight

    335.96
  • Molecular formula

    C18H37NO2.HCl
  • Storage instructions

    Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.
  • Solubility overview

    Soluble in ethanol
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    Cl.O=C(CCCCCCCCCCCCCCC)C(N)CO
  • Source

    Synthetic

References

This product has been referenced in:

  • Lowther J  et al. Structural, mechanistic and regulatory studies of serine palmitoyltransferase. Biochem Soc Trans 40:547-54 (2012). Read more (PubMed: 22616865) »
  • Bahtiar A  et al. Identification of a novel L-serine analog that suppresses osteoclastogenesis in vitro and bone turnover in vivo. J Biol Chem 284:34157-66 (2009). Read more (PubMed: 19837662) »
  • Chigorno V  et al. Activity of 3-ketosphinganine synthase during differentiation and aging of neuronal cells in culture. J Lipid Res 38:1163-9 (1997). Read more (PubMed: 9215544) »

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