3-(Methylamino)propanenitrile, lysyl oxidase enzyme inhibitor (ab144778)

Overview

  • Product name

    3-(Methylamino)propanenitrile, lysyl oxidase enzyme inhibitor
  • Description

    Irreversible lysyl oxidase enzyme inhibitor
  • Biological description

    Irreversible lysyl oxidase enzyme inhibitor (Ki = 6 μM). Antirheumatic. Active in vivo and in vitro.
  • CAS Number

    693-05-0
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    3-(Methylamino)propanenitrile
  • Molecular weight

    82.14
  • Molecular formula

    C4H8N2
  • PubChem identifier

    69656
  • Storage instructions

    Store at +4°C. The product can be stored for up to 12 months.
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    CNCCC#N
  • Source

    Synthetic

  • Research areas

References

This product has been referenced in:

  • Bondareva A  et al. The lysyl oxidase inhibitor, beta-aminopropionitrile, diminishes the metastatic colonization potential of circulating breast cancer cells. PLoS One 4:e5620 (2009). Read more (PubMed: 19440335) »
  • Wilmarth KR & Froines JR In vitro and in vivo inhibition of lysyl oxidase by aminopropionitriles. J Toxicol Environ Health 37:411-23 (1992). Read more (PubMed: 1359158) »
  • Tang SS  et al. Reaction of aortic lysyl oxidase with beta-aminopropionitrile. J Biol Chem 258:4331-8 (1983). Read more (PubMed: 6131892) »
  • Trnavský K & Trnavská Z The effect of antirheumatic drugs on the extractable collagen in lathyric chick embryos. J Pharm Pharmacol 20:564-6 (1968). Read more (PubMed: 4386865) »

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Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES, NOT FOR USE IN HUMANS"
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