3-Nitro-1-pyrenol (1-nitropyrene-3-ol), Mutagenic agent (ab144788)

Overview

  • Product name

    3-Nitro-1-pyrenol (1-nitropyrene-3-ol), Mutagenic agent
  • Description

    Mutagenic agent
  • Alternative names

    • 1-nitropyrene-3-ol
  • Biological description

    Mutagenic agent. Specific CYP3A4 metabolite of 1-nitropyrene. Putative genotoxic agent.
  • CAS Number

    86674-49-9
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    3-Nitropyren-1-ol
  • Molecular weight

    263.25
  • Molecular formula

    C16H9NO3
  • PubChem identifier

    104936
  • Storage instructions

    Store at Room Temperature. The product can be stored for up to 12 months.
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    C1=CC2=C3C(=C1)C=CC4=C(C=C(C(=C43)C=C2)[N+](=O)[O-])O
  • Source

    Synthetic

  • Research areas

References

This product has been referenced in:

  • Fullove TP  et al. Structure-dependent lipid peroxidation by photoirradiation of pyrene and its mono-substituted derivatives. J Environ Sci Health A Tox Hazard Subst Environ En 48:233-41 (2013). Read more (PubMed: 23245298) »
  • García-Berríos ZI & Arce R Photodegradation mechanisms of 1-nitropyrene, an environmental pollutant: the effect of organic solvents, water, oxygen, phenols, and polycyclic aromatics on the destruction and product yields. J Phys Chem A 116:3652-64 (2012). Read more (PubMed: 22458822) »
  • Howard PC  et al. Oxidative metabolism of 1-nitropyrene by rabbit liver microsomes and purified microsomal cytochrome P-450 isozymes. Cancer Res 48:4261-5 (1988). Read more (PubMed: 3390822) »

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