3,3'-Dipropylthiadicarbocyanine iodide, Fluorogenic probe (ab145407)

Overview

  • Product name

    3,3'-Dipropylthiadicarbocyanine iodide, Fluorogenic probe
  • Description

    Fluorogenic probe for transmembrane potential measurements.
  • Alternative names

    • 3,3'-Di-n-propylthiadicarbocyanine iodide
    • 3-Propyl-2-[5-[3-propyl-2(3H)-benzothiazolylidene]-1,3-pentadienyl]benzothiazolium iodide
    • 5-(3-Propylbenzothiazol-2-ylidene)-1-(3-propylbenzothiazolium-2-yl)-1,3-pentadiene Iodide
    • diS-C3-(5)
    • DiSC3(5)
    see all
  • Biological description

    Fluorogenic probe used to detect and measure changes in transmembrane potential or configuration induced by membrane altering agents.

  • Purity

    > 98%
  • General notes

    Fluorescence: λex 500 nm; λem 705 nm in DMF.

  • CAS Number

    53213-94-8
  • Chemical structure

    Chemical Structure

Properties

  • Excitation

    500nm
  • Emission

    705nm
  • Molecular weight

    546.53
  • Molecular formula

    C25H27IN2S2
  • Storage instructions

    Store at Room Temperature. Store under desiccating conditions. The product can be stored for up to 12 months.
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • Source

    Synthetic

References

This product has been referenced in:

  • Farrelly E  et al. A high-throughput assay for mitochondrial membrane potential in permeabilized yeast cells. Anal Biochem 293:269-76 (2001). Read more (PubMed: 11399043) »
  • Zhang GJ  et al. Influence of membrane physical state on the lysosomal proton permeability. J Membr Biol 175:53-62 (2000). Read more (PubMed: 10811967) »
  • Síp M  et al. Transmembrane potential measurement with carbocyanine dye diS-C3-(5): fast fluorescence decay studies. J Photochem Photobiol B 4:321-8 (1990). Read more (PubMed: 2107293) »
  • Smith TC  et al. The effect of the fluorescent probe, 3,3'-dipropylthiadicarbocyanine iodide, on the energy metabolism of Ehrlich ascites tumor cells. J Biol Chem 256:1108-10 (1981). Read more (PubMed: 7451493) »

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Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES, NOT FOR USE IN HUMANS"
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