Product name3MB-PP1, tyrosine kinase inhibitor
DescriptionSpecific tyrosine kinase inhibitor.
Uniquely specific bulky tyrosine kinase inhibitor which targets a mutant kinase version with an enlarged catalytic pocket while not interfering with wild-type Plk1.
Storage instructionsStore at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
This product has been referenced in:
- Klammer M et al. Identification of significant features by the Global Mean Rank test. PLoS One 9:e104504 (2014). Read more (PubMed: 25119995) »
- Oppermann FS et al. Combination of chemical genetics and phosphoproteomics for kinase signaling analysis enables confident identification of cellular downstream targets. Mol Cell Proteomics 11:O111.012351 (2012). Read more (PubMed: 22199227) »