Overview

  • Product name

  • Description

    Rabbit polyclonal to 4-1BBL
  • Host species

    Rabbit
  • Tested applications

    Suitable for: IHC-Pmore details
  • Species reactivity

    Reacts with: Human
  • Immunogen

    Synthetic peptide within Human 4-1BBL aa 200-250 conjugated to keyhole limpet haemocyanin. The exact sequence is proprietary.
    Sequence:

    QGRLLHLSAGQ RLGVHLHTEA RARHAWQLTQ GATVLGLFRV TPEIPAGLPS


    Database link: P41273

  • Positive control

    • Human lung carcinoma tissue.

Properties

Applications

Our Abpromise guarantee covers the use of ab203291 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/100 - 1/500. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Target

  • Function

    Cytokine that binds to TNFRSF9. Induces the proliferation of activated peripheral blood T-cells. May have a role in activation-induced cell death (AICD). May play a role in cognate interactions between T-cells and B-cells/macrophages.
  • Tissue specificity

    Expressed in brain, placenta, lung, skeletal muscle and kidney.
  • Sequence similarities

    Belongs to the tumor necrosis factor family.
  • Cellular localization

    Membrane.
  • Information by UniProt
  • Database links

  • Alternative names

    • 4 1BB L antibody
    • 4 1BB ligand antibody
    • 4 1BBL antibody
    • 4-1BB ligand antibody
    • 4-1BBL antibody
    • Cd137l antibody
    • Cd157l antibody
    • Homolog of mouse 4 1BB L antibody
    • Homolog of mouse 4 1BBL antibody
    • ILA ligand (TNF related) antibody
    • Ly63l antibody
    • Receptor 4 1BB ligand antibody
    • TNF superfamily member 9 antibody
    • TNFL9_HUMAN antibody
    • Tnfsf9 antibody
    • TNLG5A antibody
    • Tumor necrosis factor (ligand) superfamily member 9 antibody
    • Tumor necrosis factor ligand 5A antibody
    • Tumor necrosis factor ligand superfamily member 9 antibody
    • Tumor necrosis factor superfamily member 9 antibody
    see all

Images

  • Immunohistochemical analysis of formalin-fixed, paraffin-embedded human lung carcinoma tissue labeling 4-1BBL with ab203291 at 1/200 dilution followed by conjugation to the secondary antibody and DAB staining.

References

ab203291 has not yet been referenced specifically in any publications.

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