Overview

  • Product name

    Anti-4-1BBL antibody [RM0067-3H19]
    See all 4-1BBL primary antibodies
  • Description

    Rat monoclonal [RM0067-3H19] to 4-1BBL
  • Host species

    Rat
  • Tested applications

    Suitable for: WB, Flow Cytmore details
  • Species reactivity

    Reacts with: Mouse
  • Immunogen

    Recombinant fragment corresponding to Mouse 4-1BBL (extracellular).

Properties

Applications

Our Abpromise guarantee covers the use of ab86575 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/1000. Predicted molecular weight: 27 kDa.
Flow Cyt 1/50 - 1/200.

Target

  • Function

    Cytokine that binds to TNFRSF9. Induces the proliferation of activated peripheral blood T-cells. May have a role in activation-induced cell death (AICD). May play a role in cognate interactions between T-cells and B-cells/macrophages.
  • Tissue specificity

    Expressed in brain, placenta, lung, skeletal muscle and kidney.
  • Sequence similarities

    Belongs to the tumor necrosis factor family.
  • Cellular localization

    Membrane.
  • Information by UniProt
  • Database links

  • Alternative names

    • 4 1BB L antibody
    • 4 1BB ligand antibody
    • 4 1BBL antibody
    • 4-1BB ligand antibody
    • 4-1BBL antibody
    • Cd137l antibody
    • Cd157l antibody
    • Homolog of mouse 4 1BB L antibody
    • Homolog of mouse 4 1BBL antibody
    • ILA ligand (TNF related) antibody
    • Ly63l antibody
    • Receptor 4 1BB ligand antibody
    • TNF superfamily member 9 antibody
    • TNFL9_HUMAN antibody
    • Tnfsf9 antibody
    • TNLG5A antibody
    • Tumor necrosis factor (ligand) superfamily member 9 antibody
    • Tumor necrosis factor ligand 5A antibody
    • Tumor necrosis factor ligand superfamily member 9 antibody
    • Tumor necrosis factor superfamily member 9 antibody
    see all

References

This product has been referenced in:

  • Garza-Morales R  et al. A DNA Vaccine Encoding SA-4-1BBL Fused to HPV-16 E7 Antigen Has Prophylactic and Therapeutic Efficacy in a Cervical Cancer Mouse Model. Cancers (Basel) 11:N/A (2019). Read more (PubMed: 30650588) »
  • Fromm G  et al. Gp96-Ig/Costimulator (OX40L, ICOSL, or 4-1BBL) Combination Vaccine Improves T-cell Priming and Enhances Immunity, Memory, and Tumor Elimination. Cancer Immunol Res 4:766-78 (2016). Read more (PubMed: 27364122) »
See all 2 Publications for this product

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab86575.
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Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
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