4-Aminosalicylic acid (Para-aminosalicylic acid), pteridine synthetase inhibitor (ab143358)

Overview

  • Product name

    4-Aminosalicylic acid (Para-aminosalicylic acid), pteridine synthetase inhibitor
  • Description

    Competitive pteridine synthetase inhibitor
  • Alternative names

    • Para-aminosalicylic acid
  • Biological description

    Competitive pteridine synthetase inhibitor. Shows antituberculosis activity. Inhibits NF-κB and folic acid synthesis. Orally active.
  • Purity

    > 98%
  • CAS Number

    65-49-6
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    4-Amino-2-hydroxybenzoic acid
  • Molecular weight

    153.14
  • Molecular formula

    C7H7NO3
  • PubChem identifier

    4649
  • Storage instructions

    Store at Room Temperature. The product can be stored for up to 12 months.
  • Solubility overview

    Soluble in water to 10 mM
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    C1=CC(=C(C=C1N)O)C(=O)O
  • Source

    Synthetic

  • Research areas

References

This product has been referenced in:

  • Santos D  et al. Comparison between 5-aminosalicylic acid (5-ASA) and para-aminosalicylic acid (4-PAS) as potential protectors against Mn-induced neurotoxicity. Biol Trace Elem Res 152:113-6 (2013). Read more (PubMed: 23315311) »
  • Nelson M  et al. Effects of p-Aminosalicylic acid on the neurotoxicity of manganese on the dopaminergic innervation of the cilia of the lateral cells of the gill of the bivalve mollusc, Crassostrea virginica. Comp Biochem Physiol C Toxicol Pharmacol 151:264-70 (2010). Read more (PubMed: 19944778) »

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab143358.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES, NOT FOR USE IN HUMANS"
For licensing inquiries, please contact partnerships@abcam.com

Sign up