4'-Demethylepipodophyllotoxin, microtubule assembly inhibitor (ab142634)
Key features and details
- Potent microtubule assembly inhibitor. Antimitotic agent.
- CAS Number: 6559-91-7
- Purity: > 98%
- Soluble in DMSO (with warming)
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
4'-Demethylepipodophyllotoxin, microtubule assembly inhibitor -
Description
Potent microtubule assembly inhibitor. Antimitotic agent. -
Biological description
Antimitotic agent. Potent inhibitor of microtubule assembly. Antioxidant and chemopreventive effects in vivo. Orally active. -
Purity
> 98% -
CAS Number
6559-91-7 -
Chemical structure
Properties
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Chemical name
(5S,5aR,8aR,9R)-5-Hydroxy-9-(4-hydroxy-3,5-dimethoxyphenyl)-5a,6,8a,9-tetrahydro-5H-[2]benzofuro[5,6-f][1,3]benzodioxol-8-one -
Molecular weight
400.38 -
Molecular formula
C21H20O8 -
PubChem identifier
122797 -
Storage instructions
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in DMSO (with warming) -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
COC1=CC(=CC(=C1O)OC)C2C3C(COC3=O)C(C4=CC5=C(C=C24)OCO5)O -
Source
Synthetic
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Research areas
Protocols
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
References (0)
ab142634 has not yet been referenced specifically in any publications.
