Overview

  • Product name

    4-Hydroxynonenal, Lipid peroxidation marker
  • Description

    Lipid peroxidation marker
  • Purity

    > 97%
  • CAS Number

    75899-68-2
  • Chemical structure

    Chemical Structure

Properties

Images

  • Western blot results of biomarkers of protein synthesis, proteolysis and oxidative stress in the diaphragm.

    Panel B) The levels of 4-hydroxynonenal (4- HNE) were analyzed as an indicator of lipid peroxidation via Western blotting. A representative blot for 4-HNE protein conjugates is shown above the graph (Con n = 8, CMV n = 7, Ext 12 n = 8, Ext24 n = 8). C/D) Calpain (C) (Con n = 6, CMV n = 7, Ext 12 n = 7, Ext24 n = 8) and caspase-3.

References

This product has been referenced in:

  • Page S  et al. 4-Hydroxynonenal prevents NF-kappaB activation and tumor necrosis factor expression by inhibiting IkappaB phosphorylation and subsequent proteolysis. J Biol Chem 274:11611-8 (1999). Read more (PubMed: 10206970) »
  • Siems WG  et al. Metabolism of 4-hydroxynonenal, a cytotoxic lipid peroxidation product, in thymocytes as an effective secondary antioxidative defense mechanism. J Biochem 123:534-9 (1998). Read more (PubMed: 9538239) »
  • Esterbauer H  et al. Chemistry and biochemistry of 4-hydroxynonenal, malonaldehyde and related aldehydes. Free Radic Biol Med 11:81-128 (1991). Read more (PubMed: 1937131) »
See 1 Publication for this product

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