4-Methylumbelliferyl oleate, Fluorogenic substrate for lipases (ab145385)

Overview

  • Product name

    4-Methylumbelliferyl oleate, Fluorogenic substrate for lipases
  • Description

    Fluorogenic substrate for lipases, which can be used in aqueous solutions as well as several organic solvents.
  • Alternative names

    • 4-Methyl-2-oxo-2H-chromen-7-yl 9-octadecenoate
    • 4-Methyl-2-oxo-2H-chromen-7-yl oleate
    • 4-MU Oleate
    • 4-MUO
    • Oleic acid 4-methylumbelliferyl ester
    see all
  • Biological description

    Fluorogenic substrate for lipases, which can be used in aqueous solutions as well as several organic solvents.

  • Purity

    > 95%
  • General notes

    Fluorescence: λex 327 nm; λem 449 nm in 0.1 M phosphate pH 7.0, lipase.

  • CAS Number

    18323-58-5
  • Chemical structure

    Chemical Structure

Properties

  • Excitation

    327nm
  • Emission

    449nm
  • Chemical name

    4-Methyl-2-oxo-2H-chromen-7-yl 9-octadecenoate
  • Molecular weight

    440.61
  • Molecular formula

    C28H40O4
  • Storage instructions

    Store at +4°C. Store under desiccating conditions. The product can be stored for up to 12 months.
  • Solubility overview

    Soluble in DMSO
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • Source

    Synthetic

References

This product has been referenced in:

  • Ogawa A  et al. Lactobacillus gasseri SBT2055 suppresses fatty acid release through enlargement of fat emulsion size in vitro and promotes fecal fat excretion in healthy Japanese subjects. Lipids Health Dis 14:20 (2015). Read more (PubMed: 25884980) »
  • Zhang J  et al. Pancreatic lipase inhibitory activity of taraxacum officinale in vitro and in vivo. Nutr Res Pract 2:200-3 (2008). Read more (PubMed: 20016719) »
  • Tsuzuki W  et al. Effect of dimethylsulfoxide on hydrolysis of lipase. Biosci Biotechnol Biochem 65:2078-82 (2001). Read more (PubMed: 11676024) »
  • Jacks TJ & Kircher HW Fluorometric assay for the hydrolytic activity of lipase using fatty acyl esters of 4-methylumbelliferone. Anal Biochem 21:279-85 (1967). Read more (PubMed: 5582971) »

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