5-Aminolevulinic acid hydrochloride, precursor of protoporphyrin IX (ab142998)

Overview

  • Product name

    5-Aminolevulinic acid hydrochloride, precursor of protoporphyrin IX
  • Description

    Precursor of strong photosensitizing agent, protoporphyrin IX
  • Biological description

    Precursor of strong photosensitizing agent, protoporphyrin IX. Promotes synthesis and accumulation of fluorescent porphyrins in tissues, visible under a nonlaser, blue light source. Reduces fat mass and mitochondrial content of adipocytes in vivo. Orally active.

  • CAS Number

    5451-09-2
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    5-Amino-4-oxopentanoic acid hydrochloride salt
  • Molecular weight

    167.59
  • Molecular formula

    C5H9NO3.HCl
  • PubChem identifier

    123608
  • Storage instructions

    Store at +4°C. Store under desiccating conditions. The product can be stored for up to 12 months.
  • Solubility overview

    Soluble in water to 100 mM
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    C(CC(=O)O)C(=O)CN.Cl
  • Source

    Synthetic

  • Research areas

References

This product has been referenced in:

  • Sato T  et al. Type 2 diabetic conditions in Otsuka Long-Evans Tokushima Fatty rats are ameliorated by 5-aminolevulinic acid. Nutr Res 34:544-51 (2014). Read more (PubMed: 25026922) »
  • Liu WW  et al. Fluorescence identification of parathyroid glands by aminolevulinic acid hydrochloride in rats. Photomed Laser Surg 29:635-8 (2011). Read more (PubMed: 21438843) »
  • Komoike N  et al. Photodynamic diagnosis of colitis-associated dysplasia in a mouse model after oral administration of 5-aminolevulinic acid. In Vivo 27:747-53 (0). Read more (PubMed: 24292578) »

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab142998.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES, NOT FOR USE IN HUMANS"
For licensing inquiries, please contact partnerships@abcam.com

Sign up