5-Chloro-2-methyl-3-isothiazolone, PCAF histone acetyltransferase inhibitor (ab144735)

Overview

  • Product name

    5-Chloro-2-methyl-3-isothiazolone, PCAF histone acetyltransferase inhibitor
  • Description

    PCAF histone acetyltransferase inhibitor
  • Biological description

    PCAF histone acetyltransferase inhibitor (IC50 = 2-3 μM). Antimicrobial. Active in vitro.
  • CAS Number

    26172-55-4
  • Chemical structure

    Chemical Structure

Properties

References

This product has been referenced in:

  • Dekker FJ  et al. Inhibition of the PCAF histone acetyl transferase and cell proliferation by isothiazolones. Bioorg Med Chem 17:460-6 (2009). Read more (PubMed: 19111471) »
  • Stimson L  et al. Isothiazolones as inhibitors of PCAF and p300 histone acetyltransferase activity. Mol Cancer Ther 4:1521-32 (2005). Read more (PubMed: 16227401) »

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