Key features and details
- Potent adenosine A1 receptor agonist
- CAS Number: 2457-80-9
- Purity: > 98%
- Soluble in DMSO to 100 mM
- Form / State: Solid
- Source: Synthetic
Product name5'-Deoxy-5'-methylthioadenosine (Methylthioadenosine), Adenosine A1 receptor agonist
DescriptionPotent adenosine A1 receptor agonist
Potent A1 receptor agonist (Ki = 10 μM). Also an A2 receptor antagonist and potent cAMP phosphodiesterase inhibitor (Ki = 62 μM). Regulates gene expression, proliferation, differentiation and apoptosis. Anti-inflammatory agent. Orally active. Active in vivo and in vitro.
Storage instructionsStore at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.
Solubility overviewSoluble in DMSO to 100 mM
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
ab141257 has not yet been referenced specifically in any publications.