Overview

  • Product name

    5-Fluorocytosine (5-FC), antifungal agent
  • Description

    Antimycotic prodrug
  • Alternative names

    • 5-FC
  • Biological description

    Antimycotic prodrug, converted to 5-fluorouracil. Disrupts DNA and RNA synthesis. Displays antifungal and antitumor activity. Active in vivo.
  • Purity

    > 99%
  • CAS Number

    2022-85-7
  • Chemical structure

    Chemical Structure

Properties

References

This product has been referenced in:

  • Ostertag D  et al. Brain tumor eradication and prolonged survival from intratumoral conversion of 5-fluorocytosine to 5-fluorouracil using a nonlytic retroviral replicating vector. Neuro Oncol 14:145-59 (2012). Read more (PubMed: 22070930) »
  • Fuchita M  et al. Bacterial cytosine deaminase mutants created by molecular engineering show improved 5-fluorocytosine-mediated cell killing in vitro and in vivo. Cancer Res 69:4791-9 (2009). Read more (PubMed: 19487291) »
  • Hope WW  et al. Surface response modeling to examine the combination of amphotericin B deoxycholate and 5-fluorocytosine for treatment of invasive candidiasis. J Infect Dis 192:673-80 (2005). Read more (PubMed: 16028137) »

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab141197.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES, NOT FOR USE IN HUMANS"
For licensing inquiries, please contact partnerships@abcam.com

Sign up