5-Fluoroorotic acid hydrate, selective agent in yeast molecular genetics (ab146245)

Overview

  • Product name

    5-Fluoroorotic acid hydrate, selective agent in yeast molecular genetics
  • Description

    Selective agent in yeast molecular genetics.
  • Alternative names

    • 2,6-Dihydroxy-5-fluoropyrimidine-4-carboxylic acid
    • 5-Fluoro orotic acid
    • 5-fluoro-2,6-dioxo-1,2,3,6-tetrahydropyrimidine-4-carboxylic acid
    • 5-Fluoroorotic acid
    • 5-Fluorouracil-4-carboxylic acid
    • 5-FOA
    see all
  • Biological description

    Selective agent in yeast molecular genetics, useful in the selection of orotidine-5′-phosphate decarboxylase mutants of Saccharomyces cerevisiae.

  • Purity

    > 99%
  • CAS Number

    207291-81-4
  • Chemical structure

    Chemical Structure

Properties

  • Molecular weight

    174.10
  • Molecular formula

    C5H3FN2O4
  • Storage instructions

    Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • Source

    Synthetic

References

This product has been referenced in:

  • de Medeiros AS & Hoffman CS A yeast-based high-throughput screen for modulators of phosphodiesterase activity. Methods Mol Biol 1294:181-90 (2015). Read more (PubMed: 25783886) »
  • Hamedi H  et al. Generation of a Uracil Auxotroph Strain of the Probiotic Yeast Saccharomyces boulardii as a Host for the Recombinant Protein Production. Avicenna J Med Biotechnol 5:29-34 (2013). Read more (PubMed: 23626874) »
  • Boeke JD  et al. 5-Fluoroorotic acid as a selective agent in yeast molecular genetics. Methods Enzymol 154:164-75 (1987). Read more (PubMed: 3323810) »

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