Overview

  • Product name

  • Description

    Rabbit polyclonal to 5-HT-2B
  • Host species

    Rabbit
  • Tested applications

    Suitable for: IHC-Pmore details
  • Species reactivity

    Reacts with: Human
    Predicted to work with: Rabbit, Cow, Pig, Chimpanzee, Monkey, Gorilla, Common marmoset, Orangutan
  • Immunogen

    Synthetic peptide corresponding to Human 5-HT-2B.
    (Peptide available as ab204378)

  • Positive control

    • Human brain, cortex tissue.

Properties

Applications

Our Abpromise guarantee covers the use of ab140495 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P Use a concentration of 2 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Target

  • Function

    This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. Plays a role in the regulation of impulsive behavior.
  • Tissue specificity

    Expressed in brain. Higher levels of expression are observed in the cerebellum, occipital cortex and frontal cortex.
  • Sequence similarities

    Belongs to the G-protein coupled receptor 1 family.
  • Cellular localization

    Cell membrane.
  • Information by UniProt
  • Database links

  • Alternative names

    • 5 HT 2B antibody
    • 5 HT 2B receptor antibody
    • 5 HT(2B) antibody
    • 5 HT2B antibody
    • 5 hydroxytryptamine (serotonin) receptor 2B antibody
    • 5 hydroxytryptamine (serotonin) receptor 2B G protein coupled antibody
    • 5 hydroxytryptamine 2B receptor antibody
    • 5 hydroxytryptamine receptor 2B antibody
    • 5-HT-2B antibody
    • 5-HT2B antibody
    • 5-hydroxytryptamine receptor 2B antibody
    • 5HT(2B) antibody
    • 5HT2B Receptor antibody
    • 5HT2B_HUMAN antibody
    • 5HT2F antibody
    • Htr 2b antibody
    • Htr2b antibody
    • NP75 protein antibody
    • SEROTONIN 5HT2B RECEPTOR antibody
    • Serotonin receptor 2B antibody
    • Stomach fundus serotonin receptor antibody
    see all

Images

  • Immunohistochemical analysis of formalin fixed, paraffin embedded Human brain, cortex tissue labelling 5-HT-2B with ab140495 at 2 µg/ml.

References

ab140495 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

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