Anti-5-HT-2B antibody (ab140495)

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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-5-HT-2B antibody (ab140495)

    Key features and details

    • Rabbit polyclonal to 5-HT-2B
    • Suitable for: IHC-P
    • Reacts with: Human
    • Isotype: IgG

    Overview

    Properties

    Applications

    The Abpromise guarantee

    Our Abpromise guarantee covers the use of ab140495 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    Guaranteed

    Tested applications are guaranteed to work and covered by our Abpromise guarantee.

    Predicted

    Predicted to work for this combination of applications and species but not guaranteed.

    Incompatible

    Does not work for this combination of applications and species.

    Application Species
    IHC-P
    Human
    All applications
    Rabbit
    Cow
    Pig
    Chimpanzee
    Monkey
    Gorilla
    Common marmoset
    Orangutan
    Application Abreviews Notes
    IHC-P
    Use a concentration of 2 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
    Notes
    IHC-P
    Use a concentration of 2 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

    Target

    • Function

      This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. Plays a role in the regulation of impulsive behavior.

    • Tissue specificity

      Expressed in brain. Higher levels of expression are observed in the cerebellum, occipital cortex and frontal cortex.

    • Sequence similarities

      Belongs to the G-protein coupled receptor 1 family.

    • Cellular localization

      Cell membrane.
    • Information by UniProt

    • Database links

      • Alternative names

        • 5 HT 2B antibody
        • 5 HT 2B receptor antibody
        • 5 HT(2B) antibody
        • 5 HT2B antibody
        • 5 hydroxytryptamine (serotonin) receptor 2B antibody
        • 5 hydroxytryptamine (serotonin) receptor 2B G protein coupled antibody
        • 5 hydroxytryptamine 2B receptor antibody
        • 5 hydroxytryptamine receptor 2B antibody
        • 5-HT-2B antibody
        • 5-HT2B antibody
        • 5-hydroxytryptamine receptor 2B antibody
        • 5HT(2B) antibody
        • 5HT2B Receptor antibody
        • 5HT2B_HUMAN antibody
        • 5HT2F antibody
        • Htr 2b antibody
        • Htr2b antibody
        • NP75 protein antibody
        • SEROTONIN 5HT2B RECEPTOR antibody
        • Serotonin receptor 2B antibody
        • Stomach fundus serotonin receptor antibody
        see all

      Images

      • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-5-HT-2B antibody (ab140495)
        Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-5-HT-2B antibody (ab140495)

        Immunohistochemical analysis of formalin fixed, paraffin embedded Human brain, cortex tissue labelling 5-HT-2B with ab140495 at 2 µg/ml.

      References (0)

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      ab140495 has not yet been referenced specifically in any publications.

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