Anti-5-HT-2B antibody (ab140495)
Key features and details
- Rabbit polyclonal to 5-HT-2B
- Suitable for: IHC-P
- Reacts with: Human
- Isotype: IgG
Overview
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Product name
Anti-5-HT-2B antibody
See all 5-HT-2B primary antibodies -
Description
Rabbit polyclonal to 5-HT-2B -
Host species
Rabbit -
Tested Applications & Species
Application Species IHC-P Human -
Immunogen
Synthetic peptide corresponding to Human 5-HT-2B.
(Peptide available asab204378) -
Positive control
- Human brain, cortex tissue.
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. -
Storage buffer
Preservative: 0.1% Sodium azide
Constituent: 99% PBS -
Concentration information loading...
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Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab140495 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Tested applications are guaranteed to work and covered by our Abpromise guarantee.
Predicted to work for this combination of applications and species but not guaranteed.
Does not work for this combination of applications and species.
Application | Species |
---|---|
IHC-P |
Human
|
All applications |
Rabbit
Cow
Pig
Chimpanzee
Monkey
Gorilla
Common marmoset
Orangutan
|
Application | Abreviews | Notes |
---|---|---|
IHC-P |
Use a concentration of 2 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
|
Notes |
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IHC-P
Use a concentration of 2 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol. |
Target
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Function
This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. Plays a role in the regulation of impulsive behavior. -
Tissue specificity
Expressed in brain. Higher levels of expression are observed in the cerebellum, occipital cortex and frontal cortex. -
Sequence similarities
Belongs to the G-protein coupled receptor 1 family. -
Cellular localization
Cell membrane. - Information by UniProt
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Database links
- Entrez Gene: 407135 Cow
- Entrez Gene: 3357 Human
- Entrez Gene: 396837 Pig
- Omim: 601122 Human
- SwissProt: P41595 Human
- SwissProt: Q29005 Pig
- Unigene: 421649 Human
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Alternative names
- 5 HT 2B antibody
- 5 HT 2B receptor antibody
- 5 HT(2B) antibody
see all
Images
References (0)
ab140495 has not yet been referenced specifically in any publications.