Product name5-(Hydroxymethyl)-2'-deoxycytidine, Modified pyrimidine
- 5 hmdC
Modified pyrimidine capable of producing interstrand cross-links in double-stranded DNA. Used to quantify DNA hydroxymethylation levels in biological samples.
Storage instructionsStore at Room Temperature. The product can be stored for up to 12 months.
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
This product has been referenced in:
- Liu S et al. Detection of oxidation products of 5-methyl-2'-deoxycytidine in Arabidopsis DNA. PLoS One 8:e84620 (2013). Read more (PubMed: 24391970) »
- Krais AM et al. Determination of genomic 5-hydroxymethyl-2'-deoxycytidine in human DNA by capillary electrophoresis with laser induced fluorescence. Epigenetics 6:560-5 (2011). Read more (PubMed: 21593596) »