5-hydroxytryptophan (5-HTP), Serotonin precursor (ab143160)

Overview

  • Product name

    5-hydroxytryptophan (5-HTP), Serotonin precursor
  • Description

    Serotonin precursor
  • Biological description

    Serotonin precursor. Converts to 5-HT via aromatic-L-amino-acid decarboxylase with vitamin B6. Augments arousal and shows antidepressant effects in vivo. Orally active. Blood-brain barrier permeable.
  • Purity

    > 99%
  • CAS Number

    56-69-9
  • Chemical structure

    Chemical Structure

Properties

References

This product has been referenced in:

  • Gupta D  et al. Antidepressant and anti-anxiety like effects of 4i (N-(3-chloro-2-methylphenyl) quinoxalin-2-carboxamide), a novel 5-HT3 receptor antagonist in acute and chronic neurobehavioral rodent models. Eur J Pharmacol 735:59-67 (2014). Read more (PubMed: 24747753) »
  • Rahman MS & Thomas P Restoration of tryptophan hydroxylase functions and serotonin content in the Atlantic croaker hypothalamus by antioxidant treatment during hypoxic stress. Front Neurosci 8:130 (2014). Read more (PubMed: 24910592) »
  • Hirayama K  et al. Neuromodulatory control of a goal-directed decision. PLoS One 9:e102240 (2014). Read more (PubMed: 25048964) »

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