5-Methylcytidine, endogenous modified nucleoside (ab145606)

Overview

  • Product name

    5-Methylcytidine, endogenous modified nucleoside
  • Description

    Endogenous modified nucleoside. DNA methylation marker.
  • Biological description

    Endogenous modified nucleoside. DNA methylation marker. 5-methylcytosine (ab145605) derivative. 5-methyltransferase Trm4 substrate. Accumulates in uncharged histone tRNA molecules when 5-methyltransferase Trm4 is depleted.
  • Purity

    > 98%
  • CAS Number

    2140-61-6
  • Chemical structure

    Chemical Structure

Properties

References

This product has been referenced in:

  • Preston MA  et al. tRNAHis 5-methylcytidine levels increase in response to several growth arrest conditions in Saccharomyces cerevisiae. RNA 19:243-56 (2013). Read more (PubMed: 23249748) »
  • Edelheit S  et al. Transcriptome-wide mapping of 5-methylcytidine RNA modifications in bacteria, archaea, and yeast reveals m5C within archaeal mRNAs. PLoS Genet 9:e1003602 (2013). Read more (PubMed: 23825970) »
  • Chouliaras L  et al. Prevention of age-related changes in hippocampal levels of 5-methylcytidine by caloric restriction. Neurobiol Aging 33:1672-81 (2012). Read more (PubMed: 21764481) »

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