Anti-5-methylcytosine (5-mC) antibody [33D3] (ab10805)

Mouse monoclonal 5-methylcytosine (5-mC) antibody [33D3]. Validated in IP, IHC, SB, Flow Cyt, ChIP, Dot, MeDIP. Cited in 67 publication(s). Independently reviewed in 12 review(s).

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ab10805 has been referenced in 70 publications.

  • Abukiwan A  et al. Dexamethasone-induced inhibition of miR-132 via methylation promotes TGF-ß-driven progression of pancreatic cancer. Int J Oncol 54:53-64 (2019). PubMed: 30387838
  • Selli C  et al. Molecular changes during extended neoadjuvant letrozole treatment of breast cancer: distinguishing acquired resistance from dormant tumours. Breast Cancer Res 21:2 (2019). PubMed: 30616553
  • Whongsiri P  et al. Oxidative stress and LINE-1 reactivation in bladder cancer are epigenetically linked through active chromatin formation. Free Radic Biol Med 134:419-428 (2019). PubMed: 30703483
  • Cao Z  et al. Vitrification of murine mature metaphase II oocytes perturbs DNA methylation reprogramming during preimplantation embryo development. Cryobiology N/A:N/A (2019). PubMed: 30707961
  • de Souza AF  et al. Dynamics of male canine germ cell development. PLoS One 13:e0193026 (2018). PubMed: 29489867
  • Hou Z  et al. Maternal betaine administration modulates hepatic type 1 iodothyronine deiodinase (Dio1) expression in chicken offspring through epigenetic modifications. Comp Biochem Physiol B Biochem Mol Biol 218:30-36 (2018). PubMed: 29452261
  • Zou H  et al. Promoter methylation and Hoxd4 regulate UII mRNA tissue-specific expression in olive flounder (paralichthys olivaceus). Gen Comp Endocrinol 262:36-43 (2018). MeDIP . PubMed: 29522756
  • Zhao N  et al. Maternal betaine supplementation attenuates glucocorticoid-induced hepatic lipid accumulation through epigenetic modification in adult offspring rats. J Nutr Biochem 54:105-112 (2018). MeDIP . PubMed: 29331496
  • Baptissart M  et al. Multigenerational impacts of bile exposure are mediated by TGR5 signaling pathways. Sci Rep 8:16875 (2018). PubMed: 30443025
  • Wang KC  et al. Ten-eleven translocation 1 dysfunction reduces 5-hydroxymethylcytosine expression levels in gastric cancer cells. Oncol Lett 15:278-284 (2018). PubMed: 29285192
  • Ruan Z  et al. Effect of sex differences in donor foetal fibroblast on the early development and DNA methylation status of buffalo (Bubalus bubalis) nuclear transfer embryos. Reprod Domest Anim N/A:N/A (2018). PubMed: 30051521
  • Hua C  et al. Dexamethasone impacts zinc levels in goats by regulating zinc transportation in the colon and the metabolism in the liver. Anim Sci J 89:1296-1301 (2018). PubMed: 29943507
  • Laura B  et al. Epigenetic control of defense genes following MeJA-induced priming in rice (O. sativa). J Plant Physiol 228:166-177 (2018). PubMed: 29936261
  • Yang X  et al. 5-methylcytosine promotes mRNA export - NSUN2 as the methyltransferase and ALYREF as an m5C reader. Cell Res 27:606-625 (2017). PubMed: 28418038
  • Jiang D  et al. TET3-mediated DNA oxidation promotes ATR-dependent DNA damage response. EMBO Rep 18:781-796 (2017). PubMed: 28325772
  • Hoang TV  et al. Lens development requires DNMT1 but takes place normally in the absence of both DNMT3A and DNMT3B activity. Epigenetics 12:27-40 (2017). PubMed: 27824296
  • Zhu Y  et al. Maternal dietary manganese protects chick embryos against maternal heat stress via epigenetic-activated antioxidant and anti-apoptotic abilities. Oncotarget 8:89665-89680 (2017). PubMed: 29163779
  • Tian P  et al. Negative effects of long-term feeding of high-grain diets to lactating goats on milk fat production and composition by regulating gene expression and DNA methylation in the mammary gland. J Anim Sci Biotechnol 8:74 (2017). PubMed: 29026537
  • Amankulor NM  et al. Mutant IDH1 regulates the tumor-associated immune system in gliomas. Genes Dev 31:774-786 (2017). PubMed: 28465358
  • Guo J  et al. The possible molecular mechanisms of bisphenol A action on porcine early embryonic development. Sci Rep 7:8632 (2017). PubMed: 28819136
  • Stefansson OA  et al. CpG promoter methylation of the ALKBH3 alkylation repair gene in breast cancer. BMC Cancer 17:469 (2017). PubMed: 28679371
  • Pereira HS  et al. Rye (Secale cereale) supernumerary (B) chromosomes associated with heat tolerance during early stages of male sporogenesis. Ann Bot 119:325-337 (2017). PubMed: 27818381
  • Cao Z  et al. TSA and BIX-01294 Induced Normal DNA and Histone Methylation and Increased Protein Expression in Porcine Somatic Cell Nuclear Transfer Embryos. PLoS One 12:e0169092 (2017). IHC (PFA fixed) ; Pig . PubMed: 28114389
  • Rinaldi L  et al. Loss of Dnmt3a and Dnmt3b does not affect epidermal homeostasis but promotes squamous transformation through PPAR-?. Elife 6:N/A (2017). IHC-P, MeDIP ; Mouse . PubMed: 28425913
  • Zhu Y  et al. Maternal dietary zinc supplementation enhances the epigenetic-activated antioxidant ability of chick embryos from maternal normal and high temperatures. Oncotarget 8:19814-19824 (2017). IP . PubMed: 28177898
  • Jiang XY  et al. Inhibition of Gata4 and Tbx5 by Nicotine-Mediated DNA Methylation in Myocardial Differentiation. Stem Cell Reports 8:290-304 (2017). Dot blot . PubMed: 28111280
  • Hu Y  et al. In ovo injection of betaine alleviates corticosterone-induced fatty liver in chickens through epigenetic modifications. Sci Rep 7:40251 (2017). IP . PubMed: 28059170
  • Sun Q  et al. Maternal betaine supplementation during gestation modifies hippocampal expression of GR and its regulatory miRNAs in neonatal piglets. J Vet Med Sci 78:921-8 (2016). PubMed: 26875838
  • Klasic M  et al. DNA hypomethylation upregulates expression of the MGAT3 gene in HepG2 cells and leads to changes in N-glycosylation of secreted glycoproteins. Sci Rep 6:24363 (2016). IF . PubMed: 27073020
  • Ho SC  et al. Evaluating the use of a CpG free promoter for long-term recombinant protein expression stability in Chinese hamster ovary cells. BMC Biotechnol 16:71 (2016). IP . PubMed: 27756290
  • Lozano-Amado D  et al. Identification of repressive and active epigenetic marks and nuclear bodies in Entamoeba histolytica. Parasit Vectors 9:19 (2016). IF . PubMed: 26767976
  • Su R  et al. Transgenerational Glucose Intolerance of Tumor Necrosis Factor with Epigenetic Alteration in Rat Perirenal Adipose Tissue Induced by Intrauterine Hyperglycemia. J Diabetes Res 2016:4952801 (2016). PubMed: 26881249
  • Sirchia SM  et al. Epigenetic effects of chromatin remodeling agents on organotypic cultures. Epigenomics 8:341-58 (2016). PubMed: 26949823
  • Irie N  et al. SOX17 is a critical specifier of human primordial germ cell fate. Cell 160:253-68 (2015). IF . PubMed: 25543152
  • Zhang J  et al. Expression and potential role of microRNA-29b in mouse early embryo development. Cell Physiol Biochem 35:1178-87 (2015). PubMed: 25766529
  • Hu Y  et al. In Ovo injection of betaine affects hepatic cholesterol metabolism through epigenetic gene regulation in newly hatched chicks. PLoS One 10:e0122643 (2015). WB ; Chicken . PubMed: 25860502
  • Bockor VV  et al. Inhibition of DNA methylation alters chromatin organization, nuclear positioning and activity of 45S rDNA loci in cycling cells of Q. robur. PLoS One 9:e103954 (2014). ICC/IF . PubMed: 25093501
  • Cai D  et al. Betaine supplementation in maternal diet modulates the epigenetic regulation of hepatic gluconeogenic genes in neonatal piglets. PLoS One 9:e105504 (2014). IP . PubMed: 25153319
  • Cai D  et al. Maternal dietary betaine supplementation modifies hepatic expression of cholesterol metabolic genes via epigenetic mechanisms in newborn piglets. Br J Nutr 112:1459-68 (2014). PubMed: 25216241
  • Yeste A  et al. IL-21 induces IL-22 production in CD4+ T cells. Nat Commun 5:3753 (2014). IP . PubMed: 24796415
  • Wu D  et al. Uracil-DNA Glycosylase Is Involved in DNA Demethylation and Required for Embryonic Development in the Zebrafish Embryo. J Biol Chem 289:15463-15473 (2014). IHC-Fr . PubMed: 24739389
  • Zhang L  et al. Extrauterine growth restriction on pulmonary vascular endothelial dysfunction in adult male rats: the role of epigenetic mechanisms. J Hypertens 32:2188-98; discussion 2198 (2014). MeDIP ; Rat . PubMed: 25105456
  • Sui S  et al. Maternal Low-protein Diet Alters Ovarian Expression of Folliculogenic and Steroidogenic Genes and Their Regulatory MicroRNAs in Neonatal Piglets. Asian-Australas J Anim Sci 27:1695-704 (2014). IP ; Pig . PubMed: 25358362
  • Li X  et al. Dietary betaine supplementation to gestational sows enhances hippocampal IGF2 expression in newborn piglets with modified DNA methylation of the differentially methylated regions. Eur J Nutr N/A:N/A (2014). PubMed: 25410747
  • Farinelli P  et al. DNA methylation and differential gene regulation in photoreceptor cell death. Cell Death Dis 5:e1558 (2014). PubMed: 25476906
  • Keil KP  et al. DNA methylation of E-cadherin is a priming mechanism for prostate development. Dev Biol 387:142-53 (2014). IP ; Mouse . PubMed: 24503032
  • Guo X & Han F Asymmetric epigenetic modification and elimination of rDNA sequences by polyploidization in wheat. Plant Cell 26:4311-27 (2014). PubMed: 25415973
  • Ladopoulos V  et al. The Histone Methyltransferase KMT2B Is Required for RNA Polymerase II Association and Protection from DNA Methylation at the MagohB CpG Island Promoter. Mol Cell Biol 33:1383-93 (2013). ChIP . PubMed: 23358417
  • Nettersheim D  et al. Analysis of TET expression/activity and 5mC oxidation during normal and malignant germ cell development. PLoS One 8:e82881 (2013). IHC-P, Dot blot . PubMed: 24386123
  • Lee JY  et al. Hypermethylation and post-transcriptional regulation of DNA methyltransferases in the ovarian carcinomas of the laying hen. PLoS One 8:e61658 (2013). ICC/IF . PubMed: 23613894
  • Li R  et al. Glucocorticoid receptor is involved in the breed-dependent transcriptional regulation of mtDNA- and nuclear-encoded mitochondria genes in the liver of newborn piglets. BMC Vet Res 9:87 (2013). IP . PubMed: 23618392
  • Jia Y  et al. Maternal low-protein diet affects epigenetic regulation of hepatic mitochondrial DNA transcription in a sex-specific manner in newborn piglets associated with GR binding to its promoter. PLoS One 8:e63855 (2013). IP . PubMed: 23691106
  • Mould AW  et al. Smchd1 regulates a subset of autosomal genes subject to monoallelic expression in addition to being critical for X inactivation. Epigenetics Chromatin 6:19 (2013). MeDIP . PubMed: 23819640
  • Cao Z  et al. Dynamic reprogramming of 5-hydroxymethylcytosine during early porcine embryogenesis. Theriogenology N/A:N/A (2013). IHC . PubMed: 24315686
  • Wang Y  et al. CHIP/Stub1 functions as a tumor suppressor and represses NF-?B-mediated signaling in colorectal cancer. Carcinogenesis N/A:N/A (2013). IP . PubMed: 24302614
  • Yang B  et al. Methylation profiling defines an extensive field defect in histologically normal prostate tissues associated with prostate cancer. Neoplasia 15:399-408 (2013). IP . PubMed: 23555185
  • Bracht JR  et al. Cytosine methylation and hydroxymethylation mark DNA for elimination in Oxytricha trifallax. Genome Biol 13:R99 (2012). ICC/IF . PubMed: 23075511
  • Jia Y  et al. Maternal low-protein diet induces gender-dependent changes in epigenetic regulation of the glucose-6-phosphatase gene in newborn piglet liver. J Nutr 142:1659-65 (2012). PubMed: 22833655
  • Warren CL  et al. Fabrication of duplex DNA microarrays incorporating methyl-5-cytosine. Lab Chip 12:376-80 (2012). PubMed: 22139143
  • Zheng S  et al. Histone deacetylase 3 (HDAC3) participates in the transcriptional repression of the p16 (INK4a) gene in mammary gland of the female rat offspring exposed to an early-life high-fat diet. Epigenetics 7:183-90 (2012). IP . PubMed: 22395468
  • Nettersheim D  et al. NANOG promoter methylation and expression correlation during normal and malignant human germ cell development. Epigenetics 6:114-22 (2011). IHC-P . PubMed: 20930529
  • Hyldig SM  et al. Changes of DNA methylation level and spatial arrangement of primordial germ cells in embryonic day 15 to embryonic day 28 pig embryos. Biol Reprod 84:1087-93 (2011). PubMed: 21293033
  • Gerlitz G & Bustin M Efficient cell migration requires global chromatin condensation. J Cell Sci 123:2207-17 (2010). ICC/IF . PubMed: 20530575
  • Lu F  et al. Epigenetic regulation of Kaposi's sarcoma-associated herpesvirus latency by virus-encoded microRNAs that target Rta and the cellular Rbl2-DNMT pathway. J Virol 84:2697-706 (2010). MeDIP . PubMed: 20071580
  • Hughes T  et al. DNA methylome in human CD4+ T cells identifies transcriptionally repressive and non-repressive methylation peaks. Genes Immun 11:554-60 (2010). PubMed: 20463746
  • Venkatarama T  et al. Repression of zygotic gene expression in the Xenopus germline. Development 137:651-60 (2010). PubMed: 20110330
  • Ohta H  et al. Functional analysis of male mouse haploid germ cells of various differentiation stages: early and late round spermatids are functionally equivalent in producing progeny. Biol Reprod 80:511-7 (2009). PubMed: 19073998
  • Bártová E  et al. Epigenome and chromatin structure in human embryonic stem cells undergoing differentiation. Dev Dyn 237:3690-702 (2008). PubMed: 18985715
  • Xing Y  et al. Evidence for transgenerational transmission of epigenetic tumor susceptibility in Drosophila. PLoS Genet 3:1598-606 (2007). IP . PubMed: 17845077
  • Pfarr W  et al. Immunodetection of 5'-methylcytosine on Giemsa-stained chromosomes. Biotechniques 38:527-8, 530 (2005). PubMed: 15884667

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