Overview

  • Product name
    5-Nonyloxytryptamine oxalate, 5-HT1B agonist
  • Description
    Potent, selective 5-HT1B agonist
  • Biological description
    Potent, selective 5-HT1B agonist (Ki = 1 nM, selectivity over 5-HT1A > 300-fold). Polysialic acid (PSA) mimetic with neuroprotective activity in vitro.
  • Purity
    > 99%
  • CAS Number
    157798-13-5
  • Chemical structure
    Chemical Structure

Properties

  • Chemical name
    5-(Nonyloxy)-1H-indole-3-ethanamine oxalate
  • Molecular weight
    392.49
  • Molecular formula
    C19H30N2O.C2H2O4
  • PubChem identifier
    10126593
  • Storage instructions
    Store at Room Temperature. The product can be stored for up to 12 months.
  • Solubility overview
    Soluble in DMSO to 100 mM
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES
    CCCCCCCCCOC1=CC2=C(C=C1)NC=C2CCN.C(=O)(C(=O)O)O
  • Source

    Synthetic

  • Research areas

References

This product has been referenced in:
  • Loers G  et al. Nonyloxytryptamine mimics polysialic acid and modulates neuronal and glial functions in cell culture. J Neurochem 128:88-100 (2014). Read more (PubMed: 23957498) »
  • Glennon RA  et al. Binding of O-alkyl derivatives of serotonin at human 5-HT1D beta receptors. J Med Chem 39:314-22 (1996). Read more (PubMed: 8568822) »

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE, NOT FOR USE IN HUMANS"

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