Product name5-Sulfosalicylic acid dihydrate, Sulfonated salicylic acid derivative
DescriptionSulfonated salicylic acid derivative.
- 2-Hydroxy-5-sulfobenzoic Acid Dihydrate
- 3-carboxy-4-hydroxybenzenesulfonic acid
- Salicylsulfonic acid
Sulfonated salicylic acid derivative used as a metal scavenger due to its strong association with a range of metals. Forms proton-transfer dye complexes with diazo compounds such as 4-(phenyldiazenyl)aniline. Proteins are precipitated upon complexation with 5-Sulfosalicylic acid, allowing qualitative analysis of the resultant turbidity formed in a sample by these complexes leaving solution. Protein precipitation with 5-Sulfosalicylic acid has also been employed as a preparative measure for removing proteins prior to chromatographic analysis. Also used as a spray reagent for the detection of amino acids on thin layer chromatography (TLC) plates and as a doping agent for polyaniline.
Chemical name2-Hydroxy-5-sulfobenzoic acid dihydrate
Storage instructionsStore at Room Temperature. Store under desiccating conditions. The product can be stored for up to 12 months.
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
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This product has been referenced in:
- Cui M et al. 5-Sulfosalicylic acid dihydrate-based pretreatment for the modification of enzyme-linked immunoassay of fluoroquinolones in fishery products. J Immunoassay Immunochem 36:517-31 (2015). Read more (PubMed: 25611486) »
- Jin W et al. Ultrasensitive colorimetric assay of cadmium ion based on silver nanoparticles functionalized with 5-sulfosalicylic acid for wide practical applications. Analyst 140:3507-13 (2015). Read more (PubMed: 25831211) »
- Smith G et al. Proton transfer versus nontransfer in compounds of the diazo-dye precursor 4-(phenyldiazenyl)aniline (aniline yellow) with strong organic acids: the 5-sulfosalicylate and the dichroic benzenesulfonate salts, and the 1:2 adduct with 3,5-dinitrobenzoic acid. Acta Crystallogr C 65:o543-8 (2009). Read more (PubMed: 19805891) »
- Türkel N & Ozer U Salicylic acid derivatives form stable complexes with scandium(III) ion in aqueous solution. Chem Pharm Bull (Tokyo) 48:870-2 (2000). Read more (PubMed: 10866151) »