5-TRITC (Tetramethylrhodamine-5-isothiocyanate), Amine and nucleic acid reactive fluorescent probe (ab145472)

Overview

  • Product name

    5-TRITC (Tetramethylrhodamine-5-isothiocyanate), Amine and nucleic acid reactive fluorescent probe
  • Description

    Amine and nucleic acid reactive fluorescent probe
  • Biological description

    Amine and nucleic acid reactive fluorescent probe. 6-TRITC (ab145403) and 5(6)-TRITC (ab145353) S-isomer. Spectrally similar to TAMRA (ab145282, ab145438, ab145338, ab146486, ab145334, ab145433). Biodistributes covalently linked to poly(lactic-co-glycolic) acid (PLGA) and PLGA/chitosan nanoparticles after oral administration.

  • Purity

    > 95%
  • CAS Number

    80724-19-2
  • Chemical structure

    Chemical Structure

Properties

  • Excitation

    557nm
  • Emission

    576nm
  • Chemical name

    Tetramethylrhodamine-5-isothiocyanate
  • Molecular weight

    443.52
  • Molecular formula

    C25H21N3O3S
  • Storage instructions

    Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.
  • Solubility overview

    Soluble in DMSO
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    CN(C)c4cc5Oc1cc(ccc1C3(OC(=O)c2cc(\N=C=S)ccc23)c5cc4)N(C)C
  • Source

    Synthetic

  • Research areas

References

This product has been referenced in:

  • Navarro SM  et al. Biodistribution of PLGA and PLGA/chitosan nanoparticles after repeat-dose oral delivery in F344 rats for 7 days. Ther Deliv 5:1191-201 (2014). Read more (PubMed: 25491670) »
  • Alayed KM  et al. Immunostaining for rapid diagnosis of acute promyelocytic leukemia with the tetramethylrhodamine-5-isothiocyanate-conjugated anti-promyelocytic leukemia monoclonal antibody PG-M3. Arch Pathol Lab Med 137:1669-73 (2013). Read more (PubMed: 24168508) »
  • Cierniewski CS  et al. Peptide ligands can bind to distinct sites in integrin alphaIIbbeta3 and elicit different functional responses. J Biol Chem 274:16923-32 (1999). Read more (PubMed: 10358039) »

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Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES, NOT FOR USE IN HUMANS"
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