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ab21083 has been referenced in 58 publications.

  • Riaz MA  et al. Metformin enhances the radiosensitizing effect of cisplatin in non-small cell lung cancer cell lines with different cisplatin sensitivities. Sci Rep 9:1282 (2019). PubMed: 30718758
  • Guard SE  et al. The nuclear interactome of DYRK1A reveals a functional role in DNA damage repair. Sci Rep 9:6539 (2019). PubMed: 31024071
  • Wallace HA  et al. Condensin II subunit NCAPH2 associates with shelterin protein TRF1 and is required for telomere stability. J Cell Physiol N/A:N/A (2019). PubMed: 31026066
  • Afzal S  et al. Rat Glioma Cell-Based Functional Characterization of Anti-Stress and Protein Deaggregation Activities in the Marine Carotenoids, Astaxanthin and Fucoxanthin. Mar Drugs 17:N/A (2019). PubMed: 30909572
  • Victor MB  et al. Striatal neurons directly converted from Huntington's disease patient fibroblasts recapitulate age-associated disease phenotypes. Nat Neurosci 21:341-352 (2018). PubMed: 29403030
  • Tonzi P  et al. Translesion polymerase kappa-dependent DNA synthesis underlies replication fork recovery. Elife 7:N/A (2018). PubMed: 30422114
  • Bobkova E  et al. Recruitment of 53BP1 Proteins for DNA Repair and Persistence of Repair Clusters Differ for Cell Types as Detected by Single Molecule Localization Microscopy. Int J Mol Sci 19:N/A (2018). PubMed: 30469529
  • Khan MM  et al. DNA damage and neurodegenerative phenotypes in aged Ciz1 null mice. Neurobiol Aging 62:180-190 (2018). PubMed: 29154038
  • Jezkova L  et al. Particles with similar LET values generate DNA breaks of different complexity and reparability: a high-resolution microscopy analysis of ?H2AX/53BP1 foci. Nanoscale 10:1162-1179 (2018). PubMed: 29271466
  • Svobodová Kovaríková A  et al. H3K9me3 and H4K20me3 represent the epigenetic landscape for 53BP1 binding to DNA lesions. Aging (Albany NY) 10:2585-2605 (2018). PubMed: 30312172
  • Guo T  et al. Harnessing accurate non-homologous end joining for efficient precise deletion in CRISPR/Cas9-mediated genome editing. Genome Biol 19:170 (2018). PubMed: 30340517
  • Komseli ES  et al. A prototypical non-malignant epithelial model to study genome dynamics and concurrently monitor micro-RNAs and proteins in situ during oncogene-induced senescence. BMC Genomics 19:37 (2018). PubMed: 29321003
  • Toro C  et al. A recurrent de novo missense mutation in UBTF causes developmental neuroregression. Hum Mol Genet 27:691-705 (2018). PubMed: 29300972
  • Ding S  et al. STAG2 deficiency induces interferon responses via cGAS-STING pathway and restricts virus infection. Nat Commun 9:1485 (2018). PubMed: 29662124
  • Bártová E  et al. Depletion of A-type lamins and Lap2a reduces 53BP1 accumulation at UV-induced DNA lesions and Lap2a protein is responsible for compactness of irradiated chromatin. J Cell Biochem N/A:N/A (2018). PubMed: 29923310
  • Gursoy-Yuzugullu O  et al. Epigenetic therapy with inhibitors of histone methylation suppresses DNA damage signaling and increases glioma cell radiosensitivity. Oncotarget 8:24518-24532 (2017). ICC/IF ; Human . PubMed: 28445939
  • Takizawa H  et al. Pathogen-Induced TLR4-TRIF Innate Immune Signaling in Hematopoietic Stem Cells Promotes Proliferation but Reduces Competitive Fitness. Cell Stem Cell 21:225-240.e5 (2017). PubMed: 28736216
  • Solanas G  et al. Aged Stem Cells Reprogram Their Daily Rhythmic Functions to Adapt to Stress. Cell 170:678-692.e20 (2017). PubMed: 28802040
  • Zanini IM  et al. Human cactin interacts with DHX8 and SRRM2 to assure efficient pre-mRNA splicing and sister chromatid cohesion. J Cell Sci 130:767-778 (2017). PubMed: 28062851
  • Bétous R  et al. Human Adipose-Derived Stem Cells Expanded Under Ambient Oxygen Concentration Accumulate Oxidative DNA Lesions and Experience Procarcinogenic DNA Replication Stress. Stem Cells Transl Med 6:68-76 (2017). PubMed: 28170194
  • Fouquin A  et al. PARP2 controls double-strand break repair pathway choice by limiting 53BP1 accumulation at DNA damage sites and promoting end-resection. Nucleic Acids Res 45:12325-12339 (2017). ICC/IF . PubMed: 29036662
  • Fischer U  et al. Gene amplification during myogenic differentiation. Oncotarget 7:6864-77 (2016). PubMed: 26760505
  • Herrtwich L  et al. DNA Damage Signaling Instructs Polyploid Macrophage Fate in Granulomas. Cell 167:1264-1280.e18 (2016). PubMed: 28084216
  • Gu Y  et al. BRCA1-deficient breast cancer cell lines are resistant to MEK inhibitors and show distinct sensitivities to 6-thioguanine. Sci Rep 6:28217 (2016). WB, IF . PubMed: 27313062
  • Despras E  et al. Rad18-dependent SUMOylation of human specialized DNA polymerase eta is required to prevent under-replicated DNA. Nat Commun 7:13326 (2016). IF . PubMed: 27811911
  • Zhao MJ  et al. Adenovirus-mediated downregulation of the ubiquitin ligase RNF8 sensitizes bladder cancer to radiotherapy. Oncotarget 7:8956-67 (2016). IF . PubMed: 26788910
  • Ahuja AK  et al. A short G1 phase imposes constitutive replication stress and fork remodelling in mouse embryonic stem cells. Nat Commun 7:10660 (2016). Mouse . PubMed: 26876348
  • Franek M  et al. Nucleolar Reorganization Upon Site-Specific Double-Strand Break Induction. J Histochem Cytochem 64:669-686 (2016). PubMed: 27680669
  • Rybak P  et al. Low level phosphorylation of histone H2AX on serine 139 (?H2AX) is not associated with DNA double-strand breaks. Oncotarget 7:49574-49587 (2016). PubMed: 27391338
  • Hansen RK  et al. SCAI promotes DNA double-strand break repair in distinct chromosomal contexts. Nat Cell Biol 18:1357-1366 (2016). PubMed: 27820601
  • Han X  et al. CRISPR-Cas9 delivery to hard-to-transfect cells via membrane deformation. Sci Adv 1:e1500454 (2015). WB ; Human . PubMed: 26601238
  • Stixová L  et al. HP1ß-dependent recruitment of UBF1 to irradiated chromatin occurs simultaneously with CPDs. Epigenetics Chromatin 7:39 (2014). ICC/IF ; Mouse . PubMed: 25587355
  • Gu Y  et al. Suppression of BRCA1 sensitizes cells to proteasome inhibitors. Cell Death Dis 5:e1580 (2014). WB, IF . PubMed: 25522274
  • Wang M  et al. EGFR-mediated chromatin condensation protects KRAS-mutant cancer cells against ionizing radiation. Cancer Res 74:2825-34 (2014). ICC/IF ; Human . PubMed: 24648348
  • Miotto B  et al. The RBBP6/ZBTB38/MCM10 axis regulates DNA replication and common fragile site stability. Cell Rep 7:575-87 (2014). WB, ICC/IF . PubMed: 24726359
  • Pawlikowska P  et al. Defective endomitosis during megakaryopoiesis leads to thrombocytopenia in Fanca-/- mice. Blood 124:3613-23 (2014). ICC/IF ; Mouse . PubMed: 25261197
  • Klement K  et al. Opposing ISWI- and CHD-class chromatin remodeling activities orchestrate heterochromatic DNA repair. J Cell Biol 207:717-33 (2014). PubMed: 25533843
  • Suchánková J  et al. PRMT1 arginine methyltransferase accumulates in cytoplasmic bodies that respond to selective inhibition and DNA damage. Eur J Histochem 58:2389 (2014). ICC/IF . PubMed: 24998928
  • Gandhi M  et al. Homologous chromosomes move and rapidly initiate contact at the sites of double-strand breaks in genes in G0-phase human cells. Cell Cycle 12:547-52 (2013). IHC-Fr, In situ hybridization, ICC/IF ; Human . PubMed: 23370393
  • Glass M & Everett RD Components of promyelocytic leukemia nuclear bodies (ND10) act cooperatively to repress herpesvirus infection. J Virol 87:2174-85 (2013). PubMed: 23221561
  • Hernández L  et al. Increased mammogram-induced DNA damage in mammary epithelial cells aged in vitro. PLoS One 8:e63052 (2013). ICC/IF ; Human . PubMed: 23667571
  • Bétous R  et al. DNA polymerase ?-dependent DNA synthesis at stalled replication forks is important for CHK1 activation. EMBO J 32:2172-85 (2013). ICC/IF . PubMed: 23799366
  • Gaber N  et al. Fetal reprogramming and senescence in hypoplastic left heart syndrome and in human pluripotent stem cells during cardiac differentiation. Am J Pathol 183:720-34 (2013). IHC-P . PubMed: 23871585
  • El-Karim EA  et al. Krüppel-like factor 4 regulates genetic stability in mouse embryonic fibroblasts. Mol Cancer 12:89 (2013). ICC/IF . PubMed: 23919723
  • Sajesh BV  et al. Synthetic lethal targeting of superoxide dismutase 1 selectively kills RAD54B-deficient colorectal cancer cells. Genetics 195:757-67 (2013). PubMed: 24002644
  • Bergoglio V  et al. DNA synthesis by Pol ? promotes fragile site stability by preventing under-replicated DNA in mitosis. J Cell Biol 201:395-408 (2013). IF . PubMed: 23609533
  • Popuri V  et al. RECQL5 plays co-operative and complementary roles with WRN syndrome helicase. Nucleic Acids Res : (2012). ICC/IF . PubMed: 23180761
  • Xiao Y  et al. Cre-mediated stress affects sirtuin expression levels, peroxisome biogenesis and metabolism, antioxidant and proinflammatory signaling pathways. PLoS One 7:e41097 (2012). PubMed: 22829911
  • Bártová E  et al. Recruitment of Oct4 Protein to UV-Damaged Chromatin in Embryonic Stem Cells. PLoS One 6:e27281 (2011). ICC/IF ; Mouse . PubMed: 22164208
  • Takahashi M  et al. MSH3 Mediates Sensitization of Colorectal Cancer Cells to Cisplatin, Oxaliplatin, and a Poly(ADP-ribose) Polymerase Inhibitor. J Biol Chem 286:12157-65 (2011). ICC/IF ; Human . PubMed: 21285347
  • Moeller BJ  et al. Discovery of DNA repair inhibitors by combinatorial library profiling. Cancer Res 71:1816-24 (2011). PubMed: 21343400
  • Kirwan M  et al. Dyskeratosis congenita and the DNA damage response. Br J Haematol 153:634-43 (2011). ICC/IF . PubMed: 21477209
  • Noon AT  et al. 53BP1-dependent robust localized KAP-1 phosphorylation is essential for heterochromatic DNA double-strand break repair. Nat Cell Biol 12:177-84 (2010). ICC/IF ; Human, Mouse . PubMed: 20081839
  • Bouwman P  et al. 53BP1 loss rescues BRCA1 deficiency and is associated with triple-negative and BRCA-mutated breast cancers. Nat Struct Mol Biol 17:688-95 (2010). ICC/IF ; Mouse . PubMed: 20453858
  • Bauerschmidt C  et al. Cohesin promotes the repair of ionizing radiation-induced DNA double-strand breaks in replicated chromatin. Nucleic Acids Res 38:477-87 (2010). ICC/IF ; Human . PubMed: 19906707
  • Ben-Aroya S  et al. Proteasome nuclear activity affects chromosome stability by controlling the turnover of mms22, a protein important for DNA repair. PLoS Genet 6:e1000852 (2010). ICC/IF ; Human . PubMed: 20174551
  • Singh DK  et al. The involvement of human RECQL4 in DNA double-strand break repair. Aging Cell 9:358-71 (2010). ICC/IF ; Human . PubMed: 20222902
  • Bártová E  et al. Coilin is rapidly recruited to UVA-induced DNA lesions and ?-radiation affects localized movement of Cajal bodies. Nucleus 5:460-8 (0). PubMed: 24859326

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