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ab36823 has been referenced in 85 publications.

  • Stojiljkovic MR  et al. Phenotypic and functional differences between senescent and aged murine microglia. Neurobiol Aging 74:56-69 (2019). PubMed: 30439594
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  • Ren X  et al. Short-term and long-term exposure to hexavalent chromium alters 53BP1 via H3K18ac and H3K27ac. Chemosphere 229:284-294 (2019). PubMed: 31078885
  • Zhang L  et al. Astragalus Polysaccharide Inhibits Ionizing Radiation-Induced Bystander Effects by Regulating MAPK/NF-kB Signaling Pathway in Bone Mesenchymal Stem Cells (BMSCs). Med Sci Monit 24:4649-4658 (2018). PubMed: 29976920
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  • Guha M  et al. hnRNPA2 mediated acetylation reduces telomere length in response to mitochondrial dysfunction. PLoS One 13:e0206897 (2018). PubMed: 30427907
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  • Abramenkovs A & Stenerlöw B Removal of heat-sensitive clustered damaged DNA sites is independent of double-strand break repair. PLoS One 13:e0209594 (2018). PubMed: 30592737
  • Rona G  et al. PARP1-dependent recruitment of the FBXL10-RNF68-RNF2 ubiquitin ligase to sites of DNA damage controls H2A.Z loading. Elife 7:N/A (2018). PubMed: 29985131
  • Lyu G  et al. TGF-ß signaling alters H4K20me3 status via miR-29 and contributes to cellular senescence and cardiac aging. Nat Commun 9:2560 (2018). PubMed: 29967491
  • Page BDG  et al. Targeted NUDT5 inhibitors block hormone signaling in breast cancer cells. Nat Commun 9:250 (2018). PubMed: 29343827
  • Yang Y  et al. Nuclear GSK3ß induces DNA double-strand break repair by phosphorylating 53BP1 in glioblastoma. Int J Oncol 52:709-720 (2018). PubMed: 29328365
  • Jalili-Firoozinezhad S  et al. Modeling radiation injury-induced cell death and countermeasure drug responses in a human Gut-on-a-Chip. Cell Death Dis 9:223 (2018). PubMed: 29445080
  • Tiwari A  et al. 53BP1 can limit sister-chromatid rupture and rearrangements driven by a distinct ultrafine DNA bridging-breakage process. Nat Commun 9:677 (2018). PubMed: 29445165
  • Takahashi A  et al. Downregulation of cytoplasmic DNases is implicated in cytoplasmic DNA accumulation and SASP in senescent cells. Nat Commun 9:1249 (2018). PubMed: 29593264
  • Mendez-Dorantes C  et al. Repeat-mediated deletions can be induced by a chromosomal break far from a repeat, but multiple pathways suppress such rearrangements. Genes Dev 32:524-536 (2018). PubMed: 29636371
  • Gustafsson NMS  et al. Targeting PFKFB3 radiosensitizes cancer cells and suppresses homologous recombination. Nat Commun 9:3872 (2018). PubMed: 30250201
  • Ma S  et al. LncRNA BANCR promotes tumorigenesis and enhances adriamycin resistance in colorectal cancer. Aging (Albany NY) 10:2062-2078 (2018). PubMed: 30144787
  • Zhou Z  et al. Pold3 is required for genomic stability and telomere integrity in embryonic stem cells and meiosis. Nucleic Acids Res 46:3468-3486 (2018). PubMed: 29447390
  • He J  et al. miR-300 regulates cellular radiosensitivity through targeting p53 and apaf1 in human lung cancer cells. Cell Cycle 16:1943-1953 (2017). PubMed: 28895780
  • Vidi PA  et al. Personal samplers of bioavailable pesticides integrated with a hair follicle assay of DNA damage to assess environmental exposures and their associated risks in children. Mutat Res 822:27-33 (2017). PubMed: 28844239
  • Zhao W  et al. BRCA1-BARD1 promotes RAD51-mediated homologous DNA pairing. Nature 550:360-365 (2017). WB . PubMed: 28976962
  • Takahashi A  et al. Exosomes maintain cellular homeostasis by excreting harmful DNA from cells. Nat Commun 8:15287 (2017). PubMed: 28508895
  • Fu Y  et al. IFITM1 suppresses expression of human endogenous retroviruses in human embryonic stem cells. FEBS Open Bio 7:1102-1110 (2017). PubMed: 28781951
  • Onyango DO  et al. PRPF8 is important for BRCA1-mediated homologous recombination. Oncotarget 8:93319-93337 (2017). PubMed: 29212152
  • Bhargava R  et al. Contribution of canonical nonhomologous end joining to chromosomal rearrangements is enhanced by ATM kinase deficiency. Proc Natl Acad Sci U S A 114:728-733 (2017). PubMed: 28057860
  • Hollingworth R  et al. Localization of Double-Strand Break Repair Proteins to Viral Replication Compartments following Lytic Reactivation of Kaposi's Sarcoma-Associated Herpesvirus. J Virol 91:N/A (2017). PubMed: 28855246
  • Jayaraman S  et al. The nuclear mitotic apparatus protein NuMA controls rDNA transcription and mediates the nucleolar stress response in a p53-independent manner. Nucleic Acids Res 45:11725-11742 (2017). PubMed: 28981686
  • King HO  et al. RAD51 Is a Selective DNA Repair Target to Radiosensitize Glioma Stem Cells. Stem Cell Reports 8:125-139 (2017). ICC/IF . PubMed: 28076755
  • Brachova P  et al. Cytidine deaminase Apobec3a induction in fallopian epithelium after exposure to follicular fluid. Gynecol Oncol 145:577-583 (2017). PubMed: 28215840
  • Ka NL  et al. NR1D1 Recruitment to Sites of DNA Damage Inhibits Repair and Is Associated with Chemosensitivity of Breast Cancer. Cancer Res 77:2453-2463 (2017). PubMed: 28249904
  • Kariolis MS  et al. Inhibition of the GAS6/AXL pathway augments the efficacy of chemotherapies. J Clin Invest 127:183-198 (2017). ICC/IF ; Human . PubMed: 27893463
  • Pal D  et al. TGF-ß reduces DNA ds-break repair mechanisms to heighten genetic diversity and adaptability of CD44+/CD24- cancer cells. Elife 6:N/A (2017). ICC/IF ; Human . PubMed: 28092266
  • Tanikawa M  et al. The spliceosome U2 snRNP factors promote genome stability through distinct mechanisms; transcription of repair factors and R-loop processing. Oncogenesis 5:e280 (2016). ICC/IF ; Human . PubMed: 27991914
  • Onyango DO  et al. Tetratricopeptide repeat factor XAB2 mediates the end resection step of homologous recombination. Nucleic Acids Res 44:5702-16 (2016). ICC/IF . PubMed: 27084940
  • Ercilla A  et al. New origin firing is inhibited by APC/CCdh1 activation in S-phase after severe replication stress. Nucleic Acids Res 44:4745-62 (2016). ICC/IF ; Human . PubMed: 26939887
  • Kim SB  et al. Radiation promotes colorectal cancer initiation and progression by inducing senescence-associated inflammatory responses. Oncogene 35:3365-75 (2016). IHC-P ; Mouse . PubMed: 26477319
  • Musa F  et al. Dual mTORC1/2 Inhibition as a Novel Strategy for the Resensitization and Treatment of Platinum-Resistant Ovarian Cancer. Mol Cancer Ther 15:1557-67 (2016). PubMed: 27196780
  • Marchesini M  et al. PML is required for telomere stability in non-neoplastic human cells. Oncogene 35:1811-21 (2016). IF . PubMed: 26119943
  • Quereda V  et al. An essential role for Ink4 and Cip/Kip cell-cycle inhibitors in preventing replicative stress. Cell Death Differ 23:430-41 (2016). PubMed: 26292757
  • Hansen RK  et al. SCAI promotes DNA double-strand break repair in distinct chromosomal contexts. Nat Cell Biol 18:1357-1366 (2016). PubMed: 27820601
  • Zhang X  et al. Both Complexity and Location of DNA Damage Contribute to Cellular Senescence Induced by Ionizing Radiation. PLoS One 11:e0155725 (2016). IF . PubMed: 27187621
  • Ouyang S  et al. RNF8 deficiency results in neurodegeneration in mice. Neurobiol Aging 36:2850-2860 (2015). PubMed: 26256786
  • Laberge RM  et al. MTOR regulates the pro-tumorigenic senescence-associated secretory phenotype by promoting IL1A translation. Nat Cell Biol 17:1049-61 (2015). ICC/IF . PubMed: 26147250
  • Thuy le TT  et al. Cytoglobin deficiency promotes liver cancer development from hepatosteatosis through activation of the oxidative stress pathway. Am J Pathol 185:1045-60 (2015). PubMed: 25665792
  • Hollingworth R  et al. Activation of DNA Damage Response Pathways during Lytic Replication of KSHV. Viruses 7:2908-27 (2015). IF . PubMed: 26057167
  • Meena JK  et al. Telomerase abrogates aneuploidy-induced telomere replication stress, senescence and cell depletion. EMBO J 34:1371-84 (2015). IF . PubMed: 25820263
  • Wu Y  et al. EEPD1 Rescues Stressed Replication Forks and Maintains Genome Stability by Promoting End Resection and Homologous Recombination Repair. PLoS Genet 11:e1005675 (2015). WB . PubMed: 26684013
  • Carter M  et al. Crystal structure, biochemical and cellular activities demonstrate separate functions of MTH1 and MTH2. Nat Commun 6:7871 (2015). ICC/IF ; Human . PubMed: 26238318
  • Herr P  et al. A genome-wide IR-induced RAD51 foci RNAi screen identifies CDC73 involved in chromatin remodeling for DNA repair. Cell Discov 1:15034 (2015). Human . PubMed: 27462432
  • Klement K  et al. Opposing ISWI- and CHD-class chromatin remodeling activities orchestrate heterochromatic DNA repair. J Cell Biol 207:717-33 (2014). PubMed: 25533843
  • Slatter TL  et al. Smoking during pregnancy causes double-strand DNA break damage to the placenta. Hum Pathol 45:17-26 (2014). IHC-P ; Human . PubMed: 24125744
  • Luebben SW  et al. A concomitant loss of dormant origins and FANCC exacerbates genome instability by impairing DNA replication fork progression. Nucleic Acids Res 42:5605-15 (2014). WB, ICC, IHC ; Mouse . PubMed: 24589582
  • Vidi PA  et al. NuMA promotes homologous recombination repair by regulating the accumulation of the ISWI ATPase SNF2h at DNA breaks. Nucleic Acids Res 42:6365-79 (2014). ICC/IF, WB . PubMed: 24753406
  • Sarbajna S  et al. Roles of SLX1-SLX4, MUS81-EME1, and GEN1 in avoiding genome instability and mitotic catastrophe. Genes Dev 28:1124-36 (2014). Human . PubMed: 24831703
  • Muñoz MC  et al. An RNF168 fragment defective for focal accumulation at DNA damage is proficient for inhibition of homologous recombination in BRCA1 deficient cells. Nucleic Acids Res 42:7720-33 (2014). ICC/IF . PubMed: 24829461
  • Robertson AB  et al. Endonuclease G preferentially cleaves 5-hydroxymethylcytosine-modified DNA creating a substrate for recombination. Nucleic Acids Res 42:13280-93 (2014). PubMed: 25355512
  • Staples CJ  et al. Ccdc13 is a novel human centriolar satellite protein required for ciliogenesis and genome stability. J Cell Sci 127:2910-9 (2014). PubMed: 24816561
  • Dan J  et al. Rif1 maintains telomere length homeostasis of ESCs by mediating heterochromatin silencing. Dev Cell 29:7-19 (2014). PubMed: 24735877
  • Wu L  et al. BMS-345541 sensitizes MCF-7 breast cancer cells to ionizing radiation by selective inhibition of homologous recombinational repair of DNA double-strand breaks. Radiat Res 179:160-70 (2013). PubMed: 23259762
  • Frame FM  et al. HDAC inhibitor confers radiosensitivity to prostate stem-like cells. Br J Cancer 109:3023-33 (2013). ICC . PubMed: 24220693
  • Chatterjee P  et al. PARP inhibition sensitizes to low dose-rate radiation TMPRSS2-ERG fusion gene-expressing and PTEN-deficient prostate cancer cells. PLoS One 8:e60408 (2013). ICC/IF ; Human . PubMed: 23565244
  • Meyer B  et al. Clustered DNA damage induces pan-nuclear H2AX phosphorylation mediated by ATM and DNA-PK. Nucleic Acids Res 41:6109-18 (2013). PubMed: 23620287
  • Izumiya Y  et al. Kaposi's sarcoma-associated herpesvirus K-Rta exhibits SUMO-targeting ubiquitin ligase (STUbL) like activity and is essential for viral reactivation. PLoS Pathog 9:e1003506 (2013). PubMed: 23990779
  • Chatterjee P  et al. Defective chromatin recruitment and retention of NHEJ core components in human tumor cells expressing a Cyclin E fragment. Nucleic Acids Res N/A:N/A (2013). PubMed: 24021630
  • Luebben SW  et al. Helq acts in parallel to Fancc to suppress replication-associated genome instability. Nucleic Acids Res N/A:N/A (2013). PubMed: 24005041
  • Enervald E  et al. A regulatory role for the cohesin loader NIPBL in nonhomologous end joining during immunoglobulin class switch recombination. J Exp Med 210:2503-13 (2013). Flow Cyt ; Human . PubMed: 24145515
  • Furia L  et al. A computational platform for robotized fluorescence microscopy (II): DNA damage, replication, checkpoint activation, and cell cycle progression by high-content high-resolution multiparameter image-cytometry. Cytometry A 83:344-55 (2013). PubMed: 23463591
  • Chen J & Herrup K Glutamine acts as a neuroprotectant against DNA damage, beta-amyloid and H2O2-induced stress. PLoS One 7:e33177 (2012). WB ; Mouse . PubMed: 22413000
  • Hellevik T  et al. Cancer-associated fibroblasts from human NSCLC survive ablative doses of radiation but their invasive capacity is reduced. Radiat Oncol 7:59 (2012). ICC/IF ; Human . PubMed: 22500976
  • Jones MJ  et al. Dysregulation of DNA polymerase ? recruitment to replication forks results in genomic instability. EMBO J 31:908-18 (2012). WB ; Human . PubMed: 22157819
  • Ge H  et al. Dexamethasone reduces sensitivity to cisplatin by blunting p53-dependent cellular senescence in non-small cell lung cancer. PLoS One 7:e51821 (2012). IF . PubMed: 23272171
  • Ogiwara H & Kohno T CBP and p300 histone acetyltransferases contribute to homologous recombination by transcriptionally activating the BRCA1 and RAD51 genes. PLoS One 7:e52810 (2012). Human . PubMed: 23285190
  • Muñoz MC  et al. RING finger nuclear factor RNF168 is important for defects in homologous recombination caused by loss of the breast cancer susceptibility factor BRCA1. J Biol Chem 287:40618-28 (2012). WB . PubMed: 23055523
  • Ogiwara H  et al. Histone acetylation by CBP and p300 at double-strand break sites facilitates SWI/SNF chromatin remodeling and the recruitment of non-homologous end joining factors. Oncogene 30:2135-46 (2011). PubMed: 21217779
  • Bauerschmidt C  et al. Cohesin phosphorylation and mobility of SMC1 at ionizing radiation-induced DNA double-strand breaks in human cells. Exp Cell Res 317:330-7 (2011). WB, ICC/IF ; Human . PubMed: 21056556
  • Wu L  et al. IKKß regulates the repair of DNA double-strand breaks induced by ionizing radiation in MCF-7 breast cancer cells. PLoS One 6:e18447 (2011). ICC/IF ; Human . PubMed: 21490922
  • Mehrotra PV  et al. DNA Repair Factor APLF Is a Histone Chaperone. Mol Cell 41:46-55 (2011). ICC/IF ; Human . PubMed: 21211722
  • Chen J  et al. DNA damage and cell cycle events implicate cerebellar dentate nucleus neurons as targets of Alzheimer's disease. Mol Neurodegener 5:60 (2010). IHC-P ; Human . PubMed: 21172027
  • Kim SH  et al. Androgen receptor interacts with telomeric proteins in prostate cancer cells. J Biol Chem 285:10472-6 (2010). ICC/IF ; Human . PubMed: 20110352
  • Karimi-Busheri F  et al. Senescence evasion by MCF-7 human breast tumor-initiating cells. Breast Cancer Res 12:R31 (2010). ICC/IF ; Human . PubMed: 20525204
  • Roig AI  et al. Two- and three-dimensional models for risk assessment of radiation-enhanced colorectal tumorigenesis. Radiat Res 171:33-40 (2009). IHC-P ; Human . PubMed: 19138051

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