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I am working on honey bee and interested in antibodies against Tyramine receptors. It might be that these antibodies ab85570,ab65833,ab16028, ab44635,ab60359, ab13896, ab85615, ab85937, ab102706, ab101913, ab101770, ab101914, ab102700, ab102701, might have raised against the peptide sequences that also recognize the AmTyr receptors. Could you please check if any of these antibody potentially could work on AmTyr? Below is the sequence of AmTyr receptor: gi|58585136|ref|NP_001011594.1| tyramine receptor [Apis mellifera]
Asked on Aug 24 2012
I am waiting for replies from some of the laboratories that produced these antibodies.
Of the antibodies for which we know the immunogen sequence (others are considered proprietary by the laboratories that produce the antibodies), the only two that have immunogen sequences with greater than 50% identity with the honey bee sequence you sent are:
ab85615, anti 5HT1A receptor, 77% (10/13 identical amino acids) and
ab60359, anti- 5HT4 receptor, 52% (22/42 identical amino acids).
Answered on Aug 24 2012