Overview

  • Product name

    Anti-5HT1F Receptor antibody
    See all 5HT1F Receptor primary antibodies
  • Description

    Rabbit polyclonal to 5HT1F Receptor
  • Host species

    Rabbit
  • Tested applications

    Suitable for: IHC-Pmore details
  • Species reactivity

    Reacts with: Human
    Predicted to work with: Mouse, Rabbit, Guinea pig, Cow, Chimpanzee, Gorilla, Orangutan
  • Immunogen

    Synthetic peptide corresponding to Human 5HT1F Receptor. 19 amino acid peptide from N-terminal extracellular domain of human 5HT1F Receptor.
    Database link: P30939

  • Positive control

    • IHC-P: Human kidney (renal tubules) tissue.

Properties

Applications

Our Abpromise guarantee covers the use of ab230794 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P Use a concentration of 5 - 8 µg/ml. Perform heat mediated antigen retrieval before commencing with IHC staining protocol.

Target

  • Relevance

    5HT1F is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that inhibit adenylate cyclase activity. 5HT1F is a member of the GPCR family (subfamily: Serotonin). Expression of 5HT1F has been reported in various brain structures, including cortex, hippocampus, trigeminal ganglia, and cerebral blood vessels. Expression in peripheral tissues is limited to uterus, mesentery, and artery. No expression has been detected in heart, kidney, liver, pancreas, or spleen.
  • Cellular localization

    Cell membrane; Multi pass membrane protein.
  • Database links

  • Alternative names

    • 5 HT 1F antibody
    • 5 HT1F antibody
    • 5 hydroxytryptamine (serotonin) receptor 1F antibody
    • 5 hydroxytryptamine 1F receptor antibody
    • 5 hydroxytryptamine receptor 1E beta antibody
    • 5 hydroxytryptamine receptor 1F antibody
    • 5 hydroxytryptamine serotonin receptor 1E beta antibody
    • 5 hydroxytryptamine serotonin receptor 1F antibody
    • 5HT 1F antibody
    • 5HT1F antibody
    • HGNC5292 antibody
    • HTR 1F antibody
    • HTR1EB antibody
    • HTR1EL antibody
    • HTR1F antibody
    • MR 77 antibody
    • MR77 antibody
    • Serotonin receptor 1E beta antibody
    • Serotonin receptor gene antibody
    see all

Images

  • Formalin-fixed, paraffin-embedded human kidney (renal tubules) tissue stained for 5HT1F Receptor with ab230794 at 8 μg/ml in immunohistochemical analysis.

References

ab230794 has not yet been referenced specifically in any publications.

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