Key features and details
- Rabbit polyclonal to 5HT2A Receptor
- Suitable for: IHC-P, WB
- Reacts with: Mouse, Rat
- Isotype: IgG
Product nameAnti-5HT2A Receptor antibody
See all 5HT2A Receptor primary antibodies
DescriptionRabbit polyclonal to 5HT2A Receptor
Tested applicationsSuitable for: IHC-P, WBmore details
Species reactivityReacts with: Mouse, Rat
Predicted to work with: Human
- Rat brain tissues
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We are also planning to innovate the way in which we present recommended applications and species on our product datasheets, so that only applications & species that have been tested in our own labs, our suppliers or by selected trusted collaborators are covered by our Abpromise™ guarantee.
In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
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Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
Storage bufferPreservative: 0.09% Sodium azide
Constituents: 1% BSA, 50% Glycerol
Aqueous buffered solution
Concentration information loading...
PurityProtein A purified
Our Abpromise guarantee covers the use of ab216959 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|IHC-P||1/100 - 1/500.
When using a fluorescent probe please use a dilution of 1/50 - 1/200.
FunctionThis is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. This receptor is involved in tracheal smooth muscle contraction, bronchoconstriction, and control of aldosterone production.
Sequence similaritiesBelongs to the G-protein coupled receptor 1 family.
DomainThe PDZ domain-binding motif is involved in the interaction with INADL, CASK, APBA1, DLG1 and DLG4.
Cellular localizationCell membrane. Localizes to the post-synaptic thickening of axo-dendritic synapses.
- Information by UniProt
- 5 HT 2 antibody
- 5 HT 2A antibody
- 5 HT2 receptor antibody
Anti-5HT2A Receptor antibody (ab216959) at 1/300 dilution + Mouse cerebellum lysates
Conjugated secondary antibody at 1/20000 dilution
Immunohistochemical analysis of formalin-fixed and paraffin-embedded rat brain tissue labeling 5HT2A Receptor with ab216959 at 1/200 dilution, followed by conjugation to the secondary antibody and DAB staining.
Immunohistochemical analysis of formalin-fixed and paraffin-embedded rat brain tissue labeling 5HT2A Receptor with ab216959 at 1/200 dilution, followed by conjugation to the secondary antibody Goat Anti-Rabbit IgG, Cy3 conjugated, at 1/200 dilution or 40 minutes at 37°C.
ab216959 has been referenced in 1 publication.
- Moghaddam RA et al. Evaluation of Isolated Vascular Response to 5HT1A, 5HT1B1D & 5HT2A Receptors Agonist & Antagonist in Chronic Endotoxemic Rats. Drug Res (Stuttg) N/A:N/A (2018). PubMed: 30536257