Anti-5HT2A Receptor antibody - C-terminal (ab140524)
Key features and details
- Rabbit polyclonal to 5HT2A Receptor - C-terminal
- Suitable for: IHC-P
- Reacts with: Human
- Isotype: IgG
Overview
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Product name
Anti-5HT2A Receptor antibody - C-terminal
See all 5HT2A Receptor primary antibodies -
Description
Rabbit polyclonal to 5HT2A Receptor - C-terminal -
Host species
Rabbit -
Tested applications
Suitable for: IHC-Pmore details -
Species reactivity
Reacts with: Human
Predicted to work with: Chimpanzee, Monkey, Gorilla, Common marmoset, Orangutan
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Immunogen
Synthetic peptide, corresponding to a 20 residue sequence from within C terminal amino acids of Human 5HT2A Receptor (NP_000612.1).
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Positive control
- Human placenta and adrenal tissues
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General notes
Reproducibility is key to advancing scientific discovery and accelerating scientists’ next breakthrough.
Abcam is leading the way with our range of recombinant antibodies, knockout-validated antibodies and knockout cell lines, all of which support improved reproducibility.
We are also planning to innovate the way in which we present recommended applications and species on our product datasheets, so that only applications & species that have been tested in our own labs, our suppliers or by selected trusted collaborators are covered by our Abpromise™ guarantee.
In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
Please check that this product meets your needs before purchasing. If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, as well as customer reviews and Q&As.
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. -
Storage buffer
Preservative: 0.1% Sodium azide
Constituent: 99% PBS -
Concentration information loading... -
Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
Applications
Our Abpromise guarantee covers the use of ab140524 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| Application | Abreviews | Notes |
|---|---|---|
| IHC-P | Use a concentration of 10 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol. |
Target
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Function
This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. This receptor is involved in tracheal smooth muscle contraction, bronchoconstriction, and control of aldosterone production. -
Sequence similarities
Belongs to the G-protein coupled receptor 1 family. -
Domain
The PDZ domain-binding motif is involved in the interaction with INADL, CASK, APBA1, DLG1 and DLG4. -
Cellular localization
Cell membrane. Localizes to the post-synaptic thickening of axo-dendritic synapses. - Information by UniProt
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Database links
- Entrez Gene: 3356 Human
- Omim: 182135 Human
- SwissProt: P28223 Human
- Unigene: 654586 Human
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Alternative names
- 5 HT 2 antibody
- 5 HT 2A antibody
- 5 HT2 receptor antibody
see all
Images
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-5HT2A Receptor antibody - C-terminal (ab140524)Immunohistochemical analysis of formalin fixed, paraffin embedded Human placenta tissue labelling 5HT2A Receptor with ab140524 at 10 µg/ml.
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-5HT2A Receptor antibody - C-terminal (ab140524)Immunohistochemical analysis of formalin fixed, paraffin embedded Human adrenal tissue labelling 5HT2A Receptor with ab140524 at 10 µg/ml.
References (0)
ab140524 has not yet been referenced specifically in any publications.
