Anti-5HT2A Receptor antibody - C-terminal (ab140524)
- Datasheet
- References
- Protocols
Overview
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Product name
Anti-5HT2A Receptor antibody - C-terminal
See all 5HT2A Receptor primary antibodies -
Description
Rabbit polyclonal to 5HT2A Receptor - C-terminal -
Host species
Rabbit -
Tested applications
Suitable for: IHC-Pmore details -
Species reactivity
Reacts with: Human
Predicted to work with: Chimpanzee, Monkey, Gorilla, Common marmoset, Orangutan
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Immunogen
Synthetic peptide, corresponding to a 20 residue sequence from within C terminal amino acids of Human 5HT2A Receptor (NP_000612.1).
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Positive control
- Human placenta and adrenal tissues
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. -
Storage buffer
Preservative: 0.1% Sodium azide
Constituent: 99% PBS -
Concentration information loading... -
Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
Applications
Our Abpromise guarantee covers the use of ab140524 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| Application | Abreviews | Notes |
|---|---|---|
| IHC-P | Use a concentration of 10 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol. |
Target
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Function
This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. This receptor is involved in tracheal smooth muscle contraction, bronchoconstriction, and control of aldosterone production. -
Sequence similarities
Belongs to the G-protein coupled receptor 1 family. -
Domain
The PDZ domain-binding motif is involved in the interaction with INADL, CASK, APBA1, DLG1 and DLG4. -
Cellular localization
Cell membrane. Localizes to the post-synaptic thickening of axo-dendritic synapses. - Information by UniProt
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Database links
- Entrez Gene: 3356 Human
- Omim: 182135 Human
- SwissProt: P28223 Human
- Unigene: 654586 Human
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Alternative names
- 5 HT 2 antibody
- 5 HT 2A antibody
- 5 HT2 receptor antibody
see all
Images
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-5HT2A Receptor antibody - C-terminal (ab140524)Immunohistochemical analysis of formalin fixed, paraffin embedded Human placenta tissue labelling 5HT2A Receptor with ab140524 at 10 µg/ml. -
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-5HT2A Receptor antibody - C-terminal (ab140524)Immunohistochemical analysis of formalin fixed, paraffin embedded Human adrenal tissue labelling 5HT2A Receptor with ab140524 at 10 µg/ml.
Protocols
References
ab140524 has not yet been referenced specifically in any publications.
