Product nameAnti-5HT2C Receptor antibody [EPR6486]
See all 5HT2C Receptor primary antibodies
DescriptionRabbit monoclonal [EPR6486] to 5HT2C Receptor
Tested applicationsSuitable for: WBmore details
Unsuitable for: Flow Cyt,ICC/IF,IHC-P or IP
Species reactivityReacts with: Human
Does not react with: Mouse, Rat
Synthetic peptide within Human 5HT2C Receptor aa 1-100. The exact sequence is proprietary.
- SH-SY5Y, A431 and BxPC-3 cell lysates
This product is a recombinant monoclonal antibody, which offers several advantages including:
- - High batch-to-batch consistency and reproducibility
- - Improved sensitivity and specificity
- - Long-term security of supply
- - Animal-free production
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.
Storage instructionsShipped at 4°C. Store at -20°C. Stable for 12 months at -20°C.
Dissociation constant (KD)KD = 4.06 x 10 -11 M Learn more about KD
Storage bufferpH: 7.40
Preservative: 0.05% Sodium azide
Constituents: 40% Glycerol, 9.85% Tris glycine, 50% Tissue culture supernatant
Concentration information loading...
PurityTissue culture supernatant
Our Abpromise guarantee covers the use of ab124951 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||1/1000 - 1/10000. Predicted molecular weight: 52 kDa.|
FunctionThis is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.
Sequence similaritiesBelongs to the G-protein coupled receptor 1 family.
DomainThe PDZ domain-binding motif is involved in the interaction with MPDZ.
Cellular localizationCell membrane.
- Information by UniProt
- 5 Hydroxytryptamine 2C receptor antibody
- 5-HT-1C antibody
- 5-ht-1c receptor antibody
All lanes : Anti-5HT2C Receptor antibody [EPR6486] (ab124951) at 1/1000 dilution
Lane 1 : SH-SY5Y cell lysate
Lane 2 : A431 cell lysate
Lane 3 : BxPC-3 cell lysate
Lysates/proteins at 10 µg per lane.
All lanes : standard HRP labelled goat anti-rabbit at 1/2000 dilution
Predicted band size: 52 kDa
Equilibrium disassociation constant (KD)
Learn more about KD
Click here to learn more about KD
ab124951 has not yet been referenced specifically in any publications.