Overview

  • Product name

    Anti-5HT6 Receptor antibody
    See all 5HT6 Receptor primary antibodies
  • Description

    Rabbit polyclonal to 5HT6 Receptor
  • Host species

    Rabbit
  • Tested applications

    Suitable for: IPmore details
    Unsuitable for: WB
  • Species reactivity

    Reacts with: Human
  • Immunogen

    Synthetic peptide within Human 5HT6 Receptor aa 1-50. The exact sequence is proprietary. (NP_000862.1).
    Database link: P50406

  • Positive control

    • IP: Jurkat whole cell lysate.
  • General notes

    ab241473 has not performed satisfactorily when used for WB of 5HT6 Receptor in crude preparations (e.g. whole cell lysate). This antibody can be used for WB of enriched (e.g. immunoprecipitated) sources of 5HT6 Receptor.

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
  • Storage buffer

    Preservative: 0.09% Sodium azide
    Constituent: Tris citrate/phosphate

    pH 7 to 8
  • Concentration information loading...
  • Purity

    Immunogen affinity purified
  • Purification notes

    ab241473 was affinity purified using an epitope specific to 5HT6 Receptor immobilized on solid support.
  • Clonality

    Polyclonal
  • Isotype

    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab241473 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IP Use at 2-10 µg/mg of lysate.
  • Application notes
    Is unsuitable for WB.
  • Target

    • Function

      This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that stimulate adenylate cyclase. It has a high affinity for tricyclic psychotropic drugs.
    • Tissue specificity

      Expressed in several human brain regions, most prominently in the caudate nucleus.
    • Sequence similarities

      Belongs to the G-protein coupled receptor 1 family.
    • Cellular localization

      Cell membrane.
    • Information by UniProt
    • Database links

    • Alternative names

      • 5 HT 6 antibody
      • 5 HT6 antibody
      • 5 HT6R antibody
      • 5 hydroxytryptamine (serotonin) receptor 6 G protein coupled antibody
      • 5 hydroxytryptamine 6 receptor antibody
      • 5 hydroxytryptamine receptor 6 antibody
      • 5-HT-6 antibody
      • 5-HT6 antibody
      • 5-hydroxytryptamine receptor 6 antibody
      • 5HT 6 antibody
      • 5HT6R_HUMAN antibody
      • HTR 6 antibody
      • Htr6 antibody
      • Serotonin receptor 6 antibody
      see all

    Images

    • 5HT6 Receptor was immunoprecipitated from Jurkat (human T cell leukemia cell line from peripheral blood) whole cell lysate (1 mg for IP, 20% of IP loaded) with ab241473 at 6 µg/reaction. Western blot was performed from the immunoprecipitate using ab241473 at 1 µg/ml.

      Lane 1: ab241473 IP in Jurkat whole cell lysate.
      Lane 2: Control IgG IP in Jurkat whole cell lysate.

      Detection: Chemiluminescence with exposure time of 30 seconds.

      Lysates prepared using RIPA lysis buffer.

    References

    ab241473 has not yet been referenced specifically in any publications.

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