Anti-5HT7 Receptor antibody (ab61562)
Key features and details
- Rabbit polyclonal to 5HT7 Receptor
- Suitable for: IHC-P
- Reacts with: Human
- Isotype: IgG
Overview
-
Product name
Anti-5HT7 Receptor antibody
See all 5HT7 Receptor primary antibodies -
Description
Rabbit polyclonal to 5HT7 Receptor -
Host species
Rabbit -
Tested applications
Suitable for: IHC-Pmore details -
Species reactivity
Reacts with: Human
Predicted to work with: Mouse, Rat, Horse, Guinea pig, Hamster, Cow, Dog, Pig, Monkey, Gorilla, Common marmoset, Bat
-
Immunogen
Synthetic peptide conjugated to KLH, corresponding to 19 amino acids from the 3rd cytoplasmic domain of Human 5HT7 Receptor.
-
General notes
Reproducibility is key to advancing scientific discovery and accelerating scientists’ next breakthrough.
Abcam is leading the way with our range of recombinant antibodies, knockout-validated antibodies and knockout cell lines, all of which support improved reproducibility.
We are also planning to innovate the way in which we present recommended applications and species on our product datasheets, so that only applications & species that have been tested in our own labs, our suppliers or by selected trusted collaborators are covered by our Abpromise™ guarantee.
In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
Please check that this product meets your needs before purchasing. If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, as well as customer reviews and Q&As.
Properties
-
Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
Storage buffer
pH: 7.70
Preservative: 0.1% Sodium azide
Constituent: PBS -
Concentration information loading... -
Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
-
Compatible Secondaries
-
Isotype control
Applications
Our Abpromise guarantee covers the use of ab61562 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| Application | Abreviews | Notes |
|---|---|---|
| IHC-P | Use a concentration of 10 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol. |
Target
-
Function
This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that stimulate adenylate cyclase. -
Tissue specificity
Isoform A is the predominant isoform in spleen, caudate and hippocampus. Isoform B is expressed at lower levels. Isoform D is a minor isoform in term of expression. -
Sequence similarities
Belongs to the G-protein coupled receptor 1 family. -
Cellular localization
Cell membrane. - Information by UniProt
-
Database links
- Entrez Gene: 100135549 Guinea pig
- Entrez Gene: 3363 Human
- Entrez Gene: 15566 Mouse
- Entrez Gene: 65032 Rat
- Omim: 182137 Human
- SwissProt: P50407 Guinea pig
- SwissProt: P34969 Human
- SwissProt: P32304 Mouse
see all -
Alternative names
- 5 HT 7 antibody
- 5 HT X antibody
- 5 hydroxytryptamine (serotonin) receptor 7 (adenylate cyclase coupled) antibody
see all
Images
-
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-5HT7 Receptor antibody (ab61562)Immunohistochemical analysis of formalin-fixed, paraffin-embedded Human brain cortex tissue, staining 5HT7 Receptor with ab61562 at 10 µg/ml.
References (0)
ab61562 has not yet been referenced specifically in any publications.
