Anti-5HT7 Receptor antibody (ab61823)
Key features and details
- Rabbit polyclonal to 5HT7 Receptor
- Suitable for: IHC-P
- Reacts with: Human
- Isotype: IgG
Overview
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Product name
Anti-5HT7 Receptor antibody
See all 5HT7 Receptor primary antibodies -
Description
Rabbit polyclonal to 5HT7 Receptor -
Host species
Rabbit -
Tested applications
Suitable for: IHC-Pmore details -
Species reactivity
Reacts with: Human
Predicted to work with: Mouse, Rat, Horse, Hamster, Cow, Dog, Pig, Monkey, Gorilla, Opossum, Common marmoset, Bat, Elephant
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Immunogen
Synthetic peptide conjugated to KLH, corresponding to 20 amino acids from the C-terminus of Human 5HT7 Receptor.
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Positive control
- Cerebellum
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
Storage buffer
pH: 7.70
Preservative: 0.1% Sodium azide
Constituent: PBS -
Concentration information loading... -
Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab61823 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| Application | Abreviews | Notes |
|---|---|---|
| IHC-P |
Use a concentration of 10 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
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| Notes |
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IHC-P
Use a concentration of 10 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol. |
Target
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Function
This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that stimulate adenylate cyclase. -
Tissue specificity
Isoform A is the predominant isoform in spleen, caudate and hippocampus. Isoform B is expressed at lower levels. Isoform D is a minor isoform in term of expression. -
Sequence similarities
Belongs to the G-protein coupled receptor 1 family. -
Cellular localization
Cell membrane. - Information by UniProt
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Database links
- Entrez Gene: 3363 Human
- Entrez Gene: 15566 Mouse
- Entrez Gene: 65032 Rat
- Omim: 182137 Human
- SwissProt: P34969 Human
- SwissProt: P32304 Mouse
- SwissProt: P32305 Rat
- Unigene: 73739 Human
see all -
Alternative names
- 5 HT 7 antibody
- 5 HT X antibody
- 5 hydroxytryptamine (serotonin) receptor 7 (adenylate cyclase coupled) antibody
see all
Images
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-5HT7 Receptor antibody (ab61823)Immunohistochemical analysis of formalin-fixed, paraffin-embedded Human brain cerebellum tissue, staining 5HT7 Receptor with ab61823 at 10 µg/ml.
Datasheets and documents
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SDS download
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Datasheet download
References (0)
ab61823 has not yet been referenced specifically in any publications.