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  1. Link

    5ht7-receptor-antibody-ab61823.pdf

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Neuroscience Neurotransmission Receptors / Channels GPCR Serotonin Receptors
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Anti-5HT7 Receptor antibody (ab61823)

  • Datasheet
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-5HT7 Receptor antibody (ab61823)

    Key features and details

    • Rabbit polyclonal to 5HT7 Receptor
    • Suitable for: IHC-P
    • Reacts with: Human
    • Isotype: IgG

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    Overview

    • Product name

      Anti-5HT7 Receptor antibody
      See all 5HT7 Receptor primary antibodies
    • Description

      Rabbit polyclonal to 5HT7 Receptor
    • Host species

      Rabbit
    • Tested applications

      Suitable for: IHC-Pmore details
    • Species reactivity

      Reacts with: Human
      Predicted to work with: Mouse, Rat, Horse, Hamster, Cow, Dog, Pig, Monkey, Gorilla, Opossum, Common marmoset, Bat, Elephant
    • Immunogen

      Synthetic peptide conjugated to KLH, corresponding to 20 amino acids from the C-terminus of Human 5HT7 Receptor.

    • Positive control

      • Cerebellum
    • General notes

      The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.

      If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As

    Properties

    • Form

      Liquid
    • Storage instructions

      Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
    • Storage buffer

      pH: 7.70
      Preservative: 0.1% Sodium azide
      Constituent: PBS
    • Concentration information loading...
    • Purity

      Immunogen affinity purified
    • Clonality

      Polyclonal
    • Isotype

      IgG
    • Research areas

      • Neuroscience
      • Neurotransmission
      • Receptors / Channels
      • GPCR
      • Serotonin Receptors
      • Metabolism
      • Types of disease
      • Obesity
      • Neuroscience
      • Processes

    Associated products

    • Compatible Secondaries

      • Goat Anti-Rabbit IgG H&L (Alexa Fluor® 488) (ab150077)
      • Goat Anti-Rabbit IgG H&L (HRP) (ab205718)
    • Isotype control

      • Rabbit IgG, polyclonal - Isotype Control (ChIP Grade) (ab171870)

    Applications

    The Abpromise guarantee

    Our Abpromise guarantee covers the use of ab61823 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    Application Abreviews Notes
    IHC-P
    Use a concentration of 10 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
    Notes
    IHC-P
    Use a concentration of 10 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

    Target

    • Function

      This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that stimulate adenylate cyclase.
    • Tissue specificity

      Isoform A is the predominant isoform in spleen, caudate and hippocampus. Isoform B is expressed at lower levels. Isoform D is a minor isoform in term of expression.
    • Sequence similarities

      Belongs to the G-protein coupled receptor 1 family.
    • Cellular localization

      Cell membrane.
    • Target information above from: UniProt accession P34969 The UniProt Consortium
      The Universal Protein Resource (UniProt) in 2010
      Nucleic Acids Res. 38:D142-D148 (2010) .

      Information by UniProt
    • Database links

      • Entrez Gene: 3363 Human
      • Entrez Gene: 15566 Mouse
      • Entrez Gene: 65032 Rat
      • Omim: 182137 Human
      • SwissProt: P34969 Human
      • SwissProt: P32304 Mouse
      • SwissProt: P32305 Rat
      • Unigene: 73739 Human
      • Unigene: 254266 Mouse
      • Unigene: 87132 Rat
      see all
    • Alternative names

      • 5 HT 7 antibody
      • 5 HT X antibody
      • 5 hydroxytryptamine (serotonin) receptor 7 (adenylate cyclase coupled) antibody
      • 5 hydroxytryptamine (serotonin) receptor 7 antibody
      • 5 hydroxytryptamine receptor 7 antibody
      • 5-HT-7 antibody
      • 5-HT-X antibody
      • 5-HT7 antibody
      • 5-hydroxytryptamine receptor 7 antibody
      • 5HT7 antibody
      • 5HT7R_HUMAN antibody
      • htr7 antibody
      • Serotonin 5 HT 7 receptor antibody
      • Serotonin receptor 7 antibody
      see all

    Images

    • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-5HT7 Receptor antibody (ab61823)
      Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-5HT7 Receptor antibody (ab61823)
      Immunohistochemical analysis of formalin-fixed, paraffin-embedded Human brain cerebellum tissue, staining 5HT7 Receptor with ab61823 at 10 µg/ml.

    Protocols

    • Immunohistochemistry protocols

    Click here to view the general protocols

    Datasheets and documents

    • SDS download

    • Datasheet download

      Download

    References (0)

    Publishing research using ab61823? Please let us know so that we can cite the reference in this datasheet.

    ab61823 has not yet been referenced specifically in any publications.

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