6-IAF (6-Iodoacetamidofluorescein), Thiol-reactive fluorescent label (ab145464)

Overview

  • Product name

    6-IAF (6-Iodoacetamidofluorescein), Thiol-reactive fluorescent label
  • Description

    Thiol-reactive fluorescent label
  • Biological description

    Thiol-reactive fluorescent label. Acts as an acceptor fluorophore in FRET studies with excitation and emission maxima of 347 and 530 nm respectively. 6-IATR (ab145010) derivative. Labels actin, microtubule-associated proteins and histones.

  • Purity

    > 95%
  • CAS Number

    73264-12-7
  • Chemical structure

    Chemical Structure

Properties

  • Excitation

    490nm
  • Emission

    515nm
  • Chemical name

    N-(3',6'-Dihydroxy-1-oxospiro[2-benzofuran-3,9'-xanthene]-5-yl)-2-iodoacetamide
  • Molecular weight

    515.25
  • Molecular formula

    C22H14INO6
  • PubChem identifier

    126346
  • Storage instructions

    Store at Room Temperature. Store under desiccating conditions. The product can be stored for up to 12 months.
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    C1=CC2=C(C=C1NC(=O)CI)C3(C4=C(C=C(C=C4)O)OC5=C3C=CC(=C5)O)OC2=O
  • Source

    Synthetic

  • Research areas

References

This product has been referenced in:

  • Chang YG  et al. Rhythmic ring-ring stacking drives the circadian oscillator clockwise. Proc Natl Acad Sci U S A 109:16847-51 (2012). Read more (PubMed: 22967510) »
  • Chen Y  et al. A novel allele of kaiA shortens the circadian period and strengthens interaction of oscillator components in the cyanobacterium Synechococcus elongatus PCC 7942. J Bacteriol 191:4392-400 (2009). Read more (PubMed: 19395479) »
  • Caussé E  et al. Plasma total homocysteine and other thiols analyzed by capillary electrophoresis/laser-induced fluorescence detection: comparison with two other methods. Electrophoresis 21:2074-9 (2000). Read more (PubMed: 10879969) »

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Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES, NOT FOR USE IN HUMANS"
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