7-Deazaadenosine (Tubercidin), adenosine analog antibiotic agent (ab146656)

Overview

  • Product name

    7-Deazaadenosine (Tubercidin), adenosine analog antibiotic agent
  • Description

    Adenosine analog antibiotic agent
  • Alternative names

    • 7-Deazaadenosine
  • Biological description

    Adenosine (ab120498) analog antibiotic agent. Inhibits RNA processing, nucleic acid and protein synthesis. Shows antiproliferative (IC50 = 2 nM, HEp-2 cells), antiviral (IC50 = 30 nM, poliovirus), antiparasitic and antifungal effects.
  • Purity

    > 98%
  • CAS Number

    69-33-0
  • Chemical structure

    Chemical Structure

Properties

References

This product has been referenced in:

  • De Ornellas S  et al. Design and synthesis of fluorescent 7-deazaadenosine nucleosides containing p-extended diarylacetylene motifs. Org Biomol Chem 13:68-72 (2015). Read more (PubMed: 25382270) »
  • Drew ME  et al. The adenosine analog tubercidin inhibits glycolysis in Trypanosoma brucei as revealed by an RNA interference library. J Biol Chem 278:46596-600 (2003). Read more (PubMed: 12972414) »
  • De Clercq E  et al. Nucleic acid related compounds. 51. Synthesis and biological properties of sugar-modified analogues of the nucleoside antibiotics tubercidin, toyocamycin, sangivamycin, and formycin. J Med Chem 30:481-6 (1987). Read more (PubMed: 3820218) »

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