7-Diethylaminocoumarin-3-carboxylic acid, amine and protein derivatisation reagent (ab145332)

Overview

  • Product name

    7-Diethylaminocoumarin-3-carboxylic acid, amine and protein derivatisation reagent
  • Description

    7-(Diethylamino)coumarin-3-carboxylic acid is a reagent for the derivatisation of amines and proteins. It has also been used for labelling synthetic peptides for high-throughput detection.
  • Alternative names

    • 7-(Diethylamino)-coumarin-3-carboxylic acid
    • 7-(Diethylamino)coumarin-3-carboxylic acid
    • 7-DCCA
    • DEAC
  • Biological description

    Derivatisation reagent. Fluorescent label for amine modification and protein conjugation. Also used for labeling synthetic peptides for high-throughput detection.

  • Purity

    > 98%
  • General notes

    Fluorescence: λex 409 nm; λem 473 nm in 0.1 M Tris pH 9.0.

  • CAS Number

    50995-74-9
  • Chemical structure

    Chemical Structure

Properties

  • Excitation

    409nm
  • Emission

    473nm
  • Molecular weight

    261.27
  • Molecular formula

    C14H15NO4
  • Storage instructions

    Store at Room Temperature. The product can be stored for up to 12 months.
  • Solubility overview

    Soluble in DMSO
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • Source

    Synthetic

References

This product has been referenced in:

  • Hayai A  et al. Synthesis of a fluorescence resonance energy transfer-based probe containing a tricyclic nucleoside analog for single nucleotide polymorphism typing. Bioorg Med Chem Lett 26:3552-5 (2016). Read more (PubMed: 27329795) »
  • Usui K  et al. Peptide arrays with designed alpha-helical structures for characterization of proteins from FRET fingerprint patterns. Mol Divers 8:209-18 (2004). Read more (PubMed: 15384414) »

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